Preview

Bulletin of Siberian Medicine

Advanced search

Venous thromboembolism as the first manifestation of disseminated malignancy (Trusso’s syndrome)

Abstract

A description is given of a patient with a latent tumor process that has developed recurrent thrombosis of the superficial and deep veins of the lower extremities, common iliac veins, PE, a blood clot in the right ventricle, and a spleen infarction. The examination revealed bronchogenic lung cancer with metastases to the bronchopulmonary lymph nodes and liver, confirmed by an autopsy.

About the Authors

L. I. Dvoretsky
I.M. Sechenov First Moscow State Medical University
Russian Federation

DМ, Professor, Head of the Department of Hospital Therapy No. 2,

8/2, Trubetskaya Str., Moscow, 119991



I. N. Dyadkov
S.S. Yudin City Clinical Hospital of Moscow Health Department
Russian Federation

Head of the Department of Vascular Surgery,

4, Kolomenskiy Pr., Moscow, 115446



A. P. Stepanchenko
S.S. Yudin City Clinical Hospital of Moscow Health Department
Russian Federation

PhD, Head of the X-ray Department,

4, Kolomenskiy Pr., Moscow, 115446



N. V. Dubrovskaya
I.M. Sechenov First Moscow State Medical University
Russian Federation

PhD, Assistant of the Department of Hospital Therapy № 2,

8/2, Trubetskaya Str., Moscow, 119991



References

1. Trousseau A. Phlegmasia alba dolens. In: Clinique Medicale d’Hotel-Dieu de Paris. Paris: JB Balliere et Fils, 1865; (3): 654–812.

2. Lyman G. Venous thromboembolism in the patient with cancer: Focus on burden of disease and benefits of thromboprophylaxis. Cancer. 2011; 117: 1334–1339. DOI: 10.1002/cncr.25714.

3. Khorana A. Malignancy, thrombosis and Trousseau: the case for an eponym. J. Thromb. Haemost. 2003; 1: 2463– 24655.

4. Davila M., Robles-Carrillo L., Unruh D., Huo Q., Gardiner C., Sargent I.L., Adam M., Woodhams B.J., Francis J.L., Bogdanov V.Y., Amirkhosravi A. Microparticle association and heterogeneity of tumor-derived tissue factor in plasma: is it important for coagulation activation? J. Thromb. Haemost. 2014; 12: 186–196. DOI: 10.1111/ jth.12475.

5. Matzdorff A., Riess H., Bergmann F., Bisping G., Koschmieder S., Parmentier S., Petrides P., Sosada M. Cancer Screening in Patients with Idiopathic Venous Thromboembolism – a Position Paper of the German Society of Hematology and Oncology Working Group on Hemostasis. Oncol. Res. Treat. 2015; 38: 454–458. DOI: 10.1159/000437451.

6. Robertson L., Yeoh S., Stansby G., Agarwal R. Effect of testing for cancer on cancer- and venous thromboembolism (VTE)-related mortality and morbidity in people with unprovoked VTE. Cochrane Database Syst. Rev. 2017; 23: 8. DOI: 10.1002/14651858.CD010837.pub3.


Review

For citations:


Dvoretsky L.I., Dyadkov I.N., Stepanchenko A.P., Dubrovskaya N.V. Venous thromboembolism as the first manifestation of disseminated malignancy (Trusso’s syndrome). Bulletin of Siberian Medicine. 2019;18(3):232-237. (In Russ.)

Views: 1071


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)