Neuroimaging methods for assessing the brain in diabetes mellitus (literature review)
M. V. Matveeva,
Yu. G. Samoilova,
N. G. Zhukova,
I. V. Tolmachov,
K. S. Brazovskiy,
O. P. Leiman,
N. Yu. Fimushkina,
M. A. Rotkank https://doi.org/10.20538/1682-0363-2020-2-189-194
Abstract
Diabetes mellitus (DM) is associated with changes in the structure of the brain and deterioration of cognitive functions from mild to moderate according to neuropsychological testing. With the growing DM epidemic and the increasing number of people living to old age, cognitive dysfunctions associated with DM can have serious consequences for the future of public and practical health. Chronic hyperglycemia, severe episodes of hypoglycemia, and microvascular complications are important risk factors common for type 1 and type 2 diabetes. DM is also associated with structural and functional changes in the brain, which can be diagnosed by various types of magnetic resonance imaging (MRI) of the brain. In this review, we investigate studies conducted over the past two decades to improve the understanding of how DM effects the brain function and structure. We also describe the changes characteristic of type 1 and type 2 diabetes during standard MRI, functional MRI and proton magnetic-resonance spectroscopy (proton MRS) as well as their features.
About the Authors
M. V. Matveeva
Siberian State Medical University
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
Yu. G. Samoilova
Siberian State Medical University
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
N. G. Zhukova
Siberian State Medical University
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
I. V. Tolmachov
Siberian State Medical University
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
K. S. Brazovskiy
Siberian State Medical University
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
O. P. Leiman
Siberian State Medical University
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
N. Yu. Fimushkina
Siberian State Medical University
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
M. A. Rotkank
Siberian State Medical University
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050, Russian Federation
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Review
For citations:
Matveeva M.V., Samoilova Yu.G., Zhukova N.G., Tolmachov I.V., Brazovskiy K.S., Leiman O.P., Fimushkina N.Yu., Rotkank M.A. Neuroimaging methods for assessing the brain in diabetes mellitus (literature review). Bulletin of Siberian Medicine. 2020;19(2):189-194. https://doi.org/10.20538/1682-0363-2020-2-189-194
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