Allergic rhinitis and the phenomenon of entopy

A. V. Klimov; O. V. Kalyughin; V. V. Klimov; V. S. Sviridova

doi:10.20538/1682-0363-2020-3-137-143

Allergic rhinitis and the phenomenon of entopy

A. V. Klimov, O. V. Kalyughin, V. V. Klimov, V. S. Sviridova

https://doi.org/10.20538/1682-0363-2020-3-137-143

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Abstract

This article provides a review of the phenomenon of entopy or local atopy from the viewpoint of allergic phenotypes and endotypes. A clinical form of the entopy endotype is local allergic rhinitis, which is still a fertile area for research. The exact mechanisms in the breakdown of allergen tolerance in entopy remain unclear. The review focuses on the pathogenesis, diagnostic algorithm, and the choice of treatment strategies in local allergic rhinitis.

Keywords

allergens, atopy, entopy, allergen tolerance, allergic rhinitis, local allergic rhinitis, phenotypes, endotypes, biomarkers, type 2 helper T cells, T regulatory cells

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For citations:

Klimov A.V., Kalyughin O.V., Klimov V.V., Sviridova V.S. Allergic rhinitis and the phenomenon of entopy. Bulletin of Siberian Medicine. 2020;19(3):137-143. https://doi.org/10.20538/1682-0363-2020-3-137-143

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Bulletin of Siberian Medicine

Allergic rhinitis and the phenomenon of entopy

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Bulletin of Siberian Medicine

Allergic rhinitis and the phenomenon of entopy

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