Allergic rhinitis and the phenomenon of entopy
https://doi.org/10.20538/1682-0363-2020-3-137-143
Abstract
This article provides a review of the phenomenon of entopy or local atopy from the viewpoint of allergic phenotypes and endotypes. A clinical form of the entopy endotype is local allergic rhinitis, which is still a fertile area for research. The exact mechanisms in the breakdown of allergen tolerance in entopy remain unclear. The review focuses on the pathogenesis, diagnostic algorithm, and the choice of treatment strategies in local allergic rhinitis.
About the Authors
A. V. Klimov
Siberian State Medical University
Russian Federation
2, Moscow Тrаkt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Тrаkt, Tomsk, 634050, Russian Federation
O. V. Kalyughin
Sechenov Moscow State Medical University
Russian Federation
8/2, Trubetskaya Str., Moscow, 119991, Russian Federation
Russian Federation
8/2, Trubetskaya Str., Moscow, 119991, Russian Federation
V. V. Klimov
Siberian State Medical University
Russian Federation
2, Moscow Тrаkt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Тrаkt, Tomsk, 634050, Russian Federation
V. S. Sviridova
Siberian State Medical University
Russian Federation
2, Moscow Тrаkt, Tomsk, 634050, Russian Federation
Russian Federation
2, Moscow Тrаkt, Tomsk, 634050, Russian Federation
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Review
For citations:
Klimov A.V., Kalyughin O.V., Klimov V.V., Sviridova V.S. Allergic rhinitis and the phenomenon of entopy. Bulletin of Siberian Medicine. 2020;19(3):137-143. https://doi.org/10.20538/1682-0363-2020-3-137-143
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