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Reaction of neurons of internal layers of the retina to combined influence of ionizing radiation and light

https://doi.org/10.20538/1682-0363-2006-2-96-100

Abstract

The purpose of the presented work was the establishment of a character of modifying influence of ionizing radiation on damages of neurons of internal nuclear and ganglionic layers of a retina caused by light. The investigation revealed that changes of neurons of the internal nuclear and ganglionic layers after X-ray, light (200 lk, the 1st, 2nd, 7th, 14th, 30th days) and combined influence have similar nature, but differ in a degree of expression and manifest by reactive and destructive changes of organelles. Associated neurons showed relative resistance to investigated influences in comparison with multi-polar neurons of ganglionic layer. Combined ionizing radiation and light cause substantial growth of number of hyper-chrome and picnotic multi-polar neurons of ganglionic layer of a retina. Synergic effect is mostly expressed on 7-th-14-th day of the experiment and results in progressing growth of the number of hyper chrome multi-polar neurons.

About the Authors

A. V. Potapov
Сибирский государственный медицинский университет
Russian Federation


M. V. Svetlik
Сибирский государственный медицинский университет
Russian Federation


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Review

For citations:


Potapov A.V., Svetlik M.V. Reaction of neurons of internal layers of the retina to combined influence of ionizing radiation and light. Bulletin of Siberian Medicine. 2006;5(2):96-100. (In Russ.) https://doi.org/10.20538/1682-0363-2006-2-96-100

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)