High intense of the labour is a risk factor of stress-induced left ventricular hypertrophy in engine-drivers of locomotive engines in railway transport

Abstract

Prevalence of left ventricular hypertrophy in patients in dependence on blood pressure (BP) in professional groups of patients with high and low intense of job which is comparable with prevalence of risk factors ( smoking, hypertonic disease heredity, low physical activity, high body mass) and average levels of blood pressure is studied. The study included 853 males, working (engine-drivers and their assistants) with different levels of blood pressure (normal, high normal BP and hypertension). Controls were 330 males with lower intensity of labour. Higher (19%) prevalence of left ventricular hypertrophy was shown in engine -drivers with normal and high normal BP; prevalence in controls was 1,8 and 8,3% respectively. Patients with arterial hypertension revealed no such differences. Increased level of stress induced by high intense of labour is mediated by neurohumoral influences of stress hormones on myo-cardium. This can cause the development of left ventricular hypertrophy.