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Bulletin of Siberian Medicine

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A clinical picture and treatment optimization of acute forms of tick-born encephalitis

https://doi.org/10.20538/1682-0363-2008-5-1-263-269

Abstract

A comparative clinical and serological analysis of two groups compatible by sex, age and clinical forms of acute tick-born encephalitis was conducted among 68 patients with confirmed immune enzyme method. All patients received a single injection of high titrating Russian human tick-borne encephalitis immunoglobulin by the doze varying on the patient’s weight and particular decease. All patients received symptomatic therapy as well. There were 33 patients in the group II who have been taking anaferon during two weeks since the acute period. The patients of the groups I and II didn’t have any robust alteration of the feverish period duration and cerebrospinal fluid sanitation but it was discovered that the patients of the group II with focal form had reveal predominance of IgM titer on the second week of the disease development comparing with the same indicators among the patients of the group I with focal form. The findings show the possibility to recommend anaferon for complex treatment of the patients with tick-born encephalitis in acute period.

About the Authors

M. V. Nadezhdina
Центр природно-очаговых инфекций МО «Новая больница»; Уральская государственная медицинская академия
Russian Federation


M. G. Toporkova
Центр природно-очаговых инфекций МО «Новая больница»; Уральская государственная медицинская академия
Russian Federation


N. M. Gurary
Центр природно-очаговых инфекций МО «Новая больница»; Уральская государственная медицинская академия
Russian Federation


N. A. Makhneva
Центр природно-очаговых инфекций МО «Новая больница»; Уральская государственная медицинская академия
Russian Federation


Review

For citations:


Nadezhdina M.V., Toporkova M.G., Gurary N.M., Makhneva N.A. A clinical picture and treatment optimization of acute forms of tick-born encephalitis. Bulletin of Siberian Medicine. 2008;7(5-1):263-269. (In Russ.) https://doi.org/10.20538/1682-0363-2008-5-1-263-269

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)