Immune and functional states of lymphocytes in different clinical variants of physical growth and development retardation at children and teenagers as a result of immune-endocrine correlation
https://doi.org/10.20538/1682-0363-2004-2-13-20
Abstract
For the study of hormonic-immunologic correlation a clinical model has been chosen that included two variants (somatotrophic deficiency and constitutional growth and pubertate inhibition) of physical growth and development retardation at children and teenagers. It has been revealed that immunologic changes under these dwarfism variants were of different character that reflected the hormonic effects on immunity parameters.
About the Authors
T. V. SaprinaRussian Federation
Tomsk
Ye. B. Kravets
Russian Federation
Tomsk
L. M. Ogorodova
Russian Federation
Tomsk
References
1. Акмаев И.Г. Нейроиммуноэндокринные взаимодействия: экспериментальные и клинические аспекты // Сахарный диабет. 2002. ‹ 1. С. 2—10.
2. Auernhammer C.J., Strasburger C.J. Effect of growth hormone and insulin-like growth factor I on the immune system // Eur. J. Endocrinol. 1995. V. 133. P. 635—645.
3. Badolaro R., Bond H.M., Valerio G., Petrella A. et al. Differential expression of surface membrane growth hormone receptors on human peripheral blood lymphocytes detected by dual fluorochrome flow cytometry // J. Clin. Endocrinol. Metab. 1994. V. 79. P. 984—990.
4. Berczi I. The role of growth and lactogenic hormone family in immune function // Neuroimmunomodulation. 1994. V. 1. P. 201—216.
5. Besedovsky H., Del-Rey A. Immune-neuroendocrine interactions: facts and hypotheses // Endocr. Rev. 1996. V. 17. P. 64—102.
6. Blalock J.E., Weigent D.A. Pituitary control of immune cells // Immunol. Today. 1994. V. 15. P. 39.
7. Bozzola M., De Amici M., Zecca M. et al. Modulating effect of human growth hormone on tumor necrosis factor-α and interleukin-1β // Eur. J. Endocrin. 1998. V. 138. ‹ 6. P. 640—643.
8. Burgess W., Liu Q., Zhou J., Tang Q. et al. The immune-endocrine loop during aging: role of growth hormone and insulin-like growth factor-I // Neuroimmunomodulation. 1999. V. 6. P. 56—58.
9. Clark R. The somatogenic hormones and insulin-like growth factor-1: stimulators of lymphopoiesis and immune function. // Endocr. Rev. 1997. V. 18. P. 157—179.
10. Dardenne M., Mello-Coelho V., Gagnerault M.C., Postel-Vinay M.C. Growth hormone receptors and immunocompetent cells // Ann. NY Acad. Sci. 1998. V. 840. P. 510—517.
11. Gala R.R. Prolactin and growth hormone in the regulation of the immune system // Proc. Soc. Exp. Biol. Med. 1991. V. 198. P. 513—527.
12. Geffner M. Effect of growth hormone and insulin-like growth factor I on T- and B-lymphocytes and immune function // Acta Paediatr. Suppl. 1997. V. 423. P. 76—79.
13. Gelato M.C. Aging and immune function: a possible role for growth hormone // Horm. Res. 1996. V. 45. P. 46—49.
14. Hooghe R., Delhase M., Vergani P., Malur A., Hooghe-Peters E.L. Growth hormone and prolactin are paracrine growth and differentiantion factors in the haemopoietic system. Immunol. Today. 1993. V. 14. P. 212—214.
15. Hull K.L., Thiagarajah A., Harvey S. Cellular localization of growth hormone receptors/binding proteins in immune tissues // Cell Tissue Res. 1996. V. 286. P. 69—80.
16. Kelley K.W., Arkins S., Minshall C., Liu Q., Dantzer R. Growth hormone, growth factors and hematopoiesis // Horm. Res. 1996. V. 45. P. 38—45.
17. Murphy W.J., Rui H., Longo D.L. Effects of growth hormone and prolactin on immune development and function // Life Sci. 1995. V. 57. P. 1—14.
18. Peterson B.H., Rapaport R., Henry D.P., Huseman C., Moore W.V. Effect of treatment with biosynthetic human growth hormone (GH) on peripheral blood lymphocyte populations and function in growth hormonedeficient children // J. Clin. Endocrinol. Metab. 1990. V. 70. P. 1756—1760.
19. Tatsuta T., Cheng J., Mountz J.D. Intracellular IL-1beta is an inhibitor of Fas-mediated apoptosis // J. Immunol. 1996. V. 157. P. 3949—3957.
20. Van Damme J., De Ley M., Van Snick J. Natural and recombinant human IL-1 recrptor antagonists block the effects of IL-1 on bone resorbtion and prostaglandin production // J. Immunol. 1997. V. 139. P. 1867—1872.
Review
For citations:
Saprina T.V., Kravets Ye.B., Ogorodova L.M. Immune and functional states of lymphocytes in different clinical variants of physical growth and development retardation at children and teenagers as a result of immune-endocrine correlation. Bulletin of Siberian Medicine. 2004;3(2):13-20. (In Russ.) https://doi.org/10.20538/1682-0363-2004-2-13-20