Characteristic of local antichlamydial immunity in infertile women
https://doi.org/10.20538/1682-0363-2005-4-102-106
Abstract
Objective: to determine the presence of C. trachomatis in upper genital tract and humoral immunity an laparoscopic examination in 202 patients with different infertility factors. Chlamydial persistence in endometrial and tubal tissues was correlated with circulating IgA to C.trachomatis in peritoneal fluid in tubal factor infertility (TFI) (73.5%). IgA may be recommented additional diagnostic factor of chlamydial infection of upper genital tract in TFI.
About the Authors
A. I. Novikov
Омская государственная медицинская академия
Russian Federation
Russian Federation
T. V. Klinyshkova
Омская государственная медицинская академия
Russian Federation
Russian Federation
References
1. Диагностическое значение маркеров хламидийной инфекции при осложненной, неосложненной и бессимптомной формах урогенитального хламидиоза./А.И. Епифановский, С.Ю Сидорович, Г.В Бармина. и др.//ИППП. 2003. № 3. С. 18-23.
2. Узлова Т.В., Теплова С.Н., Медведев Б.И. Роль различных микроорганизмов в генезе трубно-перитонеального бесплодия и иммунитете//ЖМЭИ. 2000. № 2. С.95-97.
3. Barlow R.E. The prevalence of Chlamydia trachomatis in fresh tissue specimens from patients with ectopic pregnancy or tubal factor infertility as determined by PCR in-situ hybridization.//J. Med. Microbiol. 2001. V.50. №10. P. 902-908.
4. Henry-Suchet J. PID: clinical and laparoscopic aspects//Ann. N. Y. Acad. Sci. 2000. V. 900. P. 301 -308.
5. Johnson N.P., Taylor K., Nadgir A.A. et al. Can diagnostic laparoscopy be avoided in routine investigation for infertility//BJOG. 2000. V. 107. N 2. P. 174-178.
6. Land J.A., Gijsen A.P., Evers J.L., Briggeman C.A. Chlamydia trachomatis in subfertile women undergoing uterine instrumentation. Screen or treat?//Hum. Reprod. 2002. V. 17. N 3. P. 525-527.
7. Mann S.N., Smith J.R., Barton S.E. Pelvic inflammatory disease//Intern. J. STD &Aids. 1996. V. 7. P. 315-321.
8. Ng E.H., Tang O.S. Ho P.C. Measurement of serum Ca-125 concentrations does not improve the value of Chlamydia trachomatis antibody in predicting tubal patology at laparoscopy//Hum. Reprod. 2001. V. 16. N 4. P. 775-77.
9. Peeling R.W., Patton D.L., Cosgrove Sweeney Y.T. et al. Antibody response to the chlamydial heat-shock protein 60 in an experimental model of chronic pelvic inflammatory disease in monkeys (Macaca nemestrina)//J. Infect. Dis. 1999. V.180. N 3. P. 774-779.
10. Thomas K., Coughlin L., Mannion P.T., Haddad N.G. The value of Chlamydia trachomatis antibody testing as part of routine infertility investigation//Hum. Reprod. 2000. V. 15. N 5. P. 1079-1082.
11. Witkin S.S., Linhares I.M. Chlamydia trachomatis in subfertile women undergoing instrumentation: an alternative to direct microbial testing or prophylactic antibiotic treatment//Hum. Reprod. 2002. V. 17. N 8. P. 1938-1941.
Review
For citations:
Novikov A.I., Klinyshkova T.V. Characteristic of local antichlamydial immunity in infertile women. Bulletin of Siberian Medicine. 2005;4(4):102-106. (In Russ.) https://doi.org/10.20538/1682-0363-2005-4-102-106
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