Cardiac disorders in burn injury
https://doi.org/10.20538/1682-0363-2020-4-198-206
Abstract
The presented review highlights the peculiarities of cardiovascular system damages in burn injury. The epidemiological data on the incidence of thermal injuries are reported. The pathogenic mechanisms of heart disorders during various periods of burn injury, as well as pathological changes in the myocardium are examined in detail. The main clinical manifestations of heart damage on the background of burn disease have been identified (heart failure, myocarditis, infectious endocarditis, cardiac arrhythmias and conduction disturbances, myocardial infarction). Special attention is paid to laboratory and instrumental methods for investigation of the heart with a discussion of the benefits and disadvantages of each method. The manuscript discusses the main therapeutic approaches for the management of burn patients with cardiac pathology, as well as the possibilities of using and the effectiveness of modern treatment methods aimed at improving survival, diminishing the severity of cardiovascular disorders and improving the prognosis of such patients.
About the Authors
N. T. Vatutin
M. Gorky Donetsk National Medical University;
V.K. Gusak Institute of Urgent and Recovery Surgery
Ukraine
Ukraine
16, Ilyicha Аv., Donetsk, 283003, Donetsk People’s Republic (Ukraine)
47, Leninsky Аv., Donetsk, 283045, Donetsk People’s Republic (Ukraine)
G. A. Ignatenko
M. Gorky Donetsk National Medical University
Ukraine
16, Ilyicha Аv., Donetsk, 283003, Donetsk People’s Republic (Ukraine)
Ukraine
16, Ilyicha Аv., Donetsk, 283003, Donetsk People’s Republic (Ukraine)
G. G. Taradin
M. Gorky Donetsk National Medical University;
V.K. Gusak Institute of Urgent and Recovery Surgery
Ukraine
Ukraine
16, Ilyicha Аv., Donetsk, 283003, Donetsk People’s Republic (Ukraine)
47, Leninsky Аv., Donetsk, 283045, Donetsk People’s Republic (Ukraine)
E. V. Eshchenko
Myrnograd Center for Primary Health Care
Ukraine
20, Sobornaya Str., Myrnograd, 85323, Ukraine
Ukraine
20, Sobornaya Str., Myrnograd, 85323, Ukraine
M. S. Goncharuk
M. Gorky Donetsk National Medical University;
V.K. Gusak Institute of Urgent and Recovery Surgery
Ukraine
Ukraine
16, Ilyicha Аv., Donetsk, 283003, Donetsk People’s Republic (Ukraine)
47, Leninsky Аv., Donetsk, 283045, Donetsk People’s Republic (Ukraine)
S. O. Kulikova
M. Gorky Donetsk National Medical University
Ukraine
16, Ilyicha Аv., Donetsk, 283003, Donetsk People’s Republic (Ukraine)
Ukraine
16, Ilyicha Аv., Donetsk, 283003, Donetsk People’s Republic (Ukraine)
References
1. Ожоги. Информационный бюллетень. Всемирная организация здравоохранения. URL: https://www.who.int/ru/newsroom/fact-sheets/detail/burns (дата обращения: 06.03.2018).
2. Greenhalgh D.G. Management of burns. N. Engl. J. Med. 2019; 380 (24): 2349–2359. DOI: 10.1056/NEJMra1807442.
3. Социально значимые заболевания населения России в 2018 г. Статистический сборник 2018 г. Министерства
4. здравоохранения Российской Федерации. URL: https://www.rosminzdrav.ru/ministry/61/22/stranitsa-9.
5. Шабанов В.Э., Деменко В.В., Савин Ю.Н., Алексеев А.А., Крутиков М.Г., Бобровников А.Э. Клинические рекомендации по оказанию медицинской помощи пострадавшим с термической в чрезвычайных ситуациях. М., 2015: 2–37.
6. Knowlin L., Reid T., Williams F., Cairns B., Charles А. Burn mortality in patients with preexisting cardiovascular disease. Burns. 2017; 43 (5): 949–955. DOI: 10.1016/j.burns.2017.01.026.
7. Culnan D.M., Capek K.D., Sheridan R.L. Etiology and prevention of multisystem organ failure. Total Burn Care. 2018; 30: 307–317. DOI: 10.1016/b978-0-323-47661-4.00030-7.
8. Nielson C.B., Duethman N.C., Howard J.M., Moncure M., Wood J.G. Burns: pathophysiology of systemic complications and current management. J. Burn Care Res. 2017; 38 (1): e469–481. DOI: 10.1097/BCR.0000000000000355.
9. Guillory A.N., Clayton R.P., Herndon D.N., Finnerty C.C. Cardiovascular dysfunction following burn injury: what we have learned from rat and mouse models. Int. J. Mol. Sci. 2016; 17 (1): 53. DOI: 10.3390/ijms17010053.
10. Coz Y.A., Aguinaga M.M., Buch K.P., Disselkamp M.A. Hospital and intensive care unit management of decompensated pulmonary hypertension and right ventricular failure. Heart Fail Rev. 2016; 21 (3): 323–346. DOI: 10.1007/s10741-015-9514-7.
11. Hur J., Yang H.T., Chun W., Kim J.H., Shin S.H., Kang H.J., Kim H.S. Inflammatory cytokines and their prognostic ability in cases of major burn injury. Ann. Lab. Med. 2015; 35 (1): 105–110. DOI: 10.3343/alm.2015.35.1.105.
12. Leung B., Younger J.F., Stockton K., Muller M., Paratz J. Cardiovascular risk profile in burn survivors. Burns. 2017; 43 (7): 1411–1417. DOI: 10.1016/j.burns.2017.07.010.
13. Szczesny B., Brunyánszki A., Ahmad A., Oláh G., Porter C., Toliver-Kinsky T., Sidossis L., Herndon D.N., Szabo C. Time-dependent and organ-specific changes in mitochondrial function, mitochondrial DNA integrity, oxidative stress and mononuclear cell infiltration in a mouse model of burn injury. PLoS One. 2015; 10 (12): e0143730. DOI: 10.1371/journal.pone.0143730.
14. Culnan D.M., Sood R. Coronary vasospasm after burn injury: first described case series of a lethal lesion. J. Burn Care Res. 2018; 39 (6): 1053–1057. DOI: 10.1093/jbcr/irx032.
15. Caliskan M., Turk E., Karagulle E., Ciftci O., Oguz H., Kostek O., Moray G., Haberal M. Coronary flow velocity reserve in burn injury: a prospective clinical cohort study. J. Burn Care Res. 2016; 37 (5): 400–408. DOI: 10.1097/BCR.0000000000000302.
16. William A., Schneider H.G., Smith C., Cleland H. The incidence and significance of raised troponin levels in acute burns. J. Burn Care Res. 2018; 39 (5): 729–735. DOI: 10.1093/jbcr/irx020.
17. Thygesen K., Alpert J.S., Jaffe A.S., Chaitman B.R., Bax J.J., Morrow D.A., White H.D.; ESC Scientific document group. Fourth universal definition of myocardial infarction (2018). Eur. Heart J. 2019; 24 (3): 237–269. DOI: 10.1093/eurheartj/ehy462.
18. Ватутин Н.Т. Тромбоэмболия легочной артерии. Донецк, 2019: 193.
19. Ватутин Н.Т., Тарадин Г.Г., Смирнова А.С., Эль-Хатиб М.А., Гриценко Ю.П., Борт Д.В., Картамышева Е.В., Гасендич Е.С. Синдром такоцубо: современное состояние проблемы. Обзор рекомендаций Ассоциации сердечной недостаточности Европейского общества кардиологов 2016. Практична ангіологія. 2016: 3 (74): 56–70.
20. Loguidice M.J., Schutt R.C., Horton J.W., Minei J.P., Keeley E.C. Heart rate variability as a predictor of death in burn patients. J. Burn Care Res. 2016; 37 (3): e227–233. DOI: 10.1097/BCR.0000000000000260.
21. Joo S.Y., Hong A.R., Lee B.C., Choi J.H., Seo C.H. Autonomic nerve activity indexed using 24-h heart rate variability in patients with burns. Burns. 2018; 44 (4): 834–840. DOI: 10.1016/j.burns.2017.12.012.
22. Пугачев М.И., Ливарский А.П., Салухов В.В., Ивченко Е.В., Харитонов М.А., Шустов С.Б. Вариабельность сердечного ритма как индикатор состояния пациентов с тяжелой ожоговой травмой. Военно-медицинский журнал. 2017: 8: 24–33.
23. Lundy J.B., Chung K.K., Pamplin J.C., Ainsworth C.R., Jeng J.C., Friedman B.C. Update on severe burn management for the intensivist. J. Intensive Care Med. 2016; 31 (8): 499–510. DOI: 10.1177/0885066615592346.
24. Abdelrahman I., Steinvall I., Elmasry M., Sjoberg F. Lidocaine infusion has a 25% opioid-sparing effect on background pain after burns: a prospective, randomised, double-blind, controlled trial. Burns. 2020; 46 (2): 465–471. DOI: 10.1016/j.burns.2019.08.010.
25. Nuñez-Villaveiran T., Sanchez M., Millan P., Garcia-de- Lorenzo A. Systematic review of the effect of propanolol on hypermetabolism in burn injuries. Med. Intensiva. 2015; 39 (2): 101–113. DOI: 10.1016/j.medin.2014.08.002.
26. Brown D.A., Gibbons J., Honari S., Klein M.B., Pham T.N., Gibran N.S. Propranolol dosing practices in adult burn patients: implications for safety and efficacy. J. Burn Care Res. 2016; 37 (3): 218–226. DOI: 10.1097/BCR.0000000000000240.
27. Guillory A.N., Herndon D.N., Silva M.B., Andersen C.R., Edgu-Fry E., Suman O.E., Finnerty C.C. Propranolol kinetics in plasma from severely burned adults. Burns. 2017; 43 (6): 1168–1174. DOI: 10.1016/j.burns.2016.10.019.
28. Manzano-Nunez R., Garcia-Perdomo H.A., Ferrada P., Ordoñez Delgado C.A., Gomez D.A., Foianini J.E. Safety and effectiveness of propranolol in severely burned patients: systematic review and meta-analysis. World J. Emerg Surg. 2017; 12: 11. DOI: 10.1186/s13017-017-0124-7.
29. Ahmadi A.R., Chicco M., Huang J., Qi L., Burdick J., Williams G.M., Cameron A.M., Sun Z. Stem cells in burn wound healing: A systematic review of the literature. Burns. 2019; 45 (5): 1014–1023. DOI: 10.1016/j.burns.2018.10.017.
30. Francis E., Kearney L., Clover J. The effects of stem cells on burn wounds: a review. Int. J. Burns Trauma. 2019; 9 (1): 1–12.
31. Li J., Zhou L., Wang Y. The effects of music intervention on burn patients during treatment procedures: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Altern. Med. 2017; 17 (1): 158. DOI: 10.1186/s12906-017-1669-4.
32. Duke J.M., Randall S.M., Fear M.W., Boyd J.H., Rea S., Wood F.M. Understanding the long-term impacts of burn on the cardiovascular system. Burns. 2016; 42 (2): 366–374. DOI: 10.1016/j.burns.2015.08.020.
33. Duke J.M., Randall S.M., Fear M.W., Boyd J.H., Rea S., Wood F.M. Long-term effects of pediatric burns on the circulatory system. Pediatrics. 2015; 136 (5): e1323–1330. DOI: 10.1542/peds.2015-1945.
Review
For citations:
Vatutin N.T., Ignatenko G.A., Taradin G.G., Eshchenko E.V., Goncharuk M.S., Kulikova S.O. Cardiac disorders in burn injury. Bulletin of Siberian Medicine. 2020;19(4):198-206. https://doi.org/10.20538/1682-0363-2020-4-198-206
Views:
2387
Email this article 