Preview

Bulletin of Siberian Medicine

Advanced search

Causal relationship between allergy and seborrheic dermatitis

https://doi.org/10.20538/1682-0363-2022-2-13-18

Abstract

Seborrheic dermatitis is a chronic relapsing inflammatory skin disease associated with overproduction of sebum and activation of the fungal skin microbiota characterized by the presence of erythematous pruritic patches and plaques with greasy scales in areas rich in sebaceous glands.

Aim. To study the spectrum of sensitization to food, pollen, and indoor and fungal allergens in patients with seborrheic dermatitis.

Materials and methods. The study researched features of the spectrum of sensitization to food, pollen, and fungal and indoor allergens in patients with seborrheic dermatitis (n = 40, aged 15–59 years) based on the data of an objective examination and the results of an allergen-specific test, including skin prick testing.

Results. It was determined that the most significant food allergens in seborrheic dermatitis are chicken eggs and grains. The incidence of polyvalent sensitization to food allergens was 40.0%. Additionally, high incidence of sensitization to pollen allergens, most often to weed and poaceae pollen, was revealed in patients with seborrheic dermatitis. Among indoor allergens, the highest incidence of sensitization was determined to house dust and Dermatophagoides pteronyssinus. Among fungal allergens, the highest incidence of sensitization was detected to Candida albicans. Conclusion. It was found that patients with seborrheic dermatitis are often sensitized to food, pollen, and indoor and fungal allergens. Therefore, allergy can be considered a risk factor for the development of pathology.

About the Authors

A. A. Barilo
Research Institute of Medical Problems of the North – a branch of the Federal Research Center Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences (KSC SB RAS)
Russian Federation

3g, Partizana Zheleznyaka Str., Krasnoyarsk, 660022



S. V. Smirnova
Research Institute of Medical Problems of the North – a branch of the Federal Research Center Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences (KSC SB RAS)
Russian Federation

3g, Partizana Zheleznyaka Str., Krasnoyarsk, 660022



References

1. Goldenberg G. Optimizing treatment approaches in seborrheic dermatitis. J Clin. Aesthet Dermatol. 2013;6(2):44–49.

2. Karabay E.A., Çerman A.A. Serum zinc levels in seborrheic dermatitis: a case-control study. Turk. J. Med. Sci. 2019;49(5):1503–1508. DOI: 10.3906/sag-1906-72.

3. Samantha R.E., Nguyen M., Vaughn A.R. The skin and gut microbiome and its role in common dermatologic conditions. Microorganisms. 2019;7(11):550. DOI: 10.3390/microorganisms7110550.

4. Чикин В.В., Минеева А.А., Заславский Д.В. Федеральные клинические рекомендации по ведению больных с себорейным дерматитом. М., 2013:15.

5. Clark G.W., Pope S.M., Jaboori K.A. Diagnosis and treatment of seborrheic dermatitis. Am. Fam. Physician. 2015;91(3):185– 190.

6. An Q., Sun M., Qi R.Q. High Staphylococcus epidermidis colonization and impaired permeability barrier in facial seborrheic dermatitis. Chin. Med. J. 2017; 130(14):1662–1669. DOI: 10.4103/0366-6999.209895.

7. Смирнова С.В., Барило А.А., Смольникова М.В. Прогностическое значение клинических и анамнестических маркеров псориатического артрита. Клиническая дерматология и венерология. 2016;15(1):23–27. DOI: 10.17116/klinderma201615123-27.

8. Барило А.А., Смирнова С.В. Роль алиментарных факторов и пищевой аллергии в развитии псориаза. Вопросы питания. 2020;89(1):60–68. DOI: 10.24411/0042-8833-2020-10002.

9. Реброва О.Ю. Статистический анализ медицинских данных. Применение пакета прикладных программ STATISTICA. М.: МедиаСфера, 2002:312.

10. Benedé S., Belen Blázquez A., Chiang D., Tordesillas L., Berin M.C. The rise of food allergy: Environmental factors and emerging treatments. EBioMedicine. 2016;7:27–34. DOI: 10.1016/j.ebiom.2016.04.012.

11. Balasasirekha. R. Food allergy: molecular basis and clinical practice. Indian J. Nutr. Diet. 2016;53(1):133. DOI: 10.21048/ijnd.2016.53.1.3881.

12. Caraballo L., Zakzuk J., Lee B.W., Acevedo N., Soh J., Sanchez-Borges M. et al. Particularities of allergy in the tropics. World Allergy Organ J. 2016:9:20. DOI: 10.1186/s40413-016-0110-7.

13. Tamer F., Yuksel M.E., Sarifakioglu E., Karabağ Y. Staphylococcus aureus is the most common bacterial agent of the skin flora of patients with seborrheic dermatitis. Dermatol. Pract. Concept. 2018;8(2):80–84. DOI: 10.5826/dpc.0802a04.

14. Dzoro S., Mittermann I., Resch-Marat Y., Vrtala S., Nehr M., Hirschl A. et al. House dust mites as potential carriers for IgE sensitization to bacterial antigens. Allergy. 2018;73(1):115– 124. DOI: 10.1111/all.13260.

15. Fukutomi Y., Taniguchi M. Sensitization to fungal allergens: Resolved and unresolved issues. Allergol Int. 2015;64(4):321– 331. DOI: 10.1016/j.alit.2015.05.007.


Review

For citations:


Barilo A.A., Smirnova S.V. Causal relationship between allergy and seborrheic dermatitis. Bulletin of Siberian Medicine. 2022;21(2):13-18. https://doi.org/10.20538/1682-0363-2022-2-13-18

Views: 5075


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)