The fibrin technologies in acceleration of damaged bone regeneration in experiment
https://doi.org/10.20538/1682-0363-2012-4-49-56
Abstract
The processes of regeneration of the damaged rat bottom jaw bone after application of enriched platelets a fibrin clot were studied by morphological and radiovisiographic methods. After operation with use of fibrin technologies already after 1 week the bone tissue defect is filled by the merged islets of again generated bone. By second week after fibrin use the further formation of bone tissue in defect and formation of a bone callosity is noted.
About the Authors
I. V. MaiborodinRussian Federation
B. V. Sheplev
M. N. Drovosekov
I. S. Kolesnikov
M. S. Toder
А. A. Shevela
References
1. Майбородин И.В., Колесников И.С., Шеплев и др. Гранулематозное воспаление после применения препаратов фибрина // Морфологические ведомости. 2007. № 3—4. С. 116—118.
2. Майбородин И.В., Колесников И.С., Шеплев Б.В. и др. Морфология подлежащих тканей десны после дентальной имплантации с применением препаратов фибрина // Стоматология. 2009. Т. 88, № 1. С. 9—13.
3. Майбородин И.В., Колесников И.С., Шеплев Б.В., Рагимова Т.М. Применение фибрина и его препаратов в стоматологии // Стоматология. 2008. Т. 87, № 6. С. 75—77.
4. Becker W. Fibrin sealants in implant and periodontal treatment: case presentations // Compend. Contin. Educ. Dent. 2005. V. 26, № 8. P. 539—545.
5. Carter G., Goss A., Lloyd J., Tocchetti R. Tranexamic acid mouthwash versus autologous fibrin glue in patients taking warfarin undergoing dental extractions: a randomized pro-spective clinical study // J. Oral Maxillofac. Surg. 2003. V. 61, № 12. P. 1432—1435.
6. Choukroun J., Diss A., Simonpieri A., Girard M.O. et al. Platelet-rich fibrin (PRF): a second-generation platelet con-centrate. Part IV: clinical effects on tissue healing // Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2006. V. 101, № 3. P. e56—e60.
7. Choukroun J., Diss A., Simonpieri A. et al. Platelet-rich fi-brin (PRF): a second-generation platelet concentrate. Part V: histologic evaluations of PRF effects on bone allograft matu-ration in sinus lift // Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2006. V. 101, № 3. P. 299—303.
8. Dohan D.M., Choukroun J., Diss A. et al. Platelet-rich fi-brin (PRF): a second-generation platelet concentrate. Part III: leucocyte activation: a new feature for platelet concentrates? // Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2006. V. 101, № 3. P. e51—e55.
9. Froum S.J., Wallace S.S., Tarnow D.P., Cho S.C. Effect of platelet-rich plasma on bone growth and osseointegration in human maxillary sinus grafts: three bilateral case reports // Int. J. Periodontics Restorative Dent. 2002. V. 22, № 1. P. 45—53.
10. Fuerst G., Gruber R., Tangl S. et al. Effects of fibrin sealant protein concentrate with and without platelet-released growth factors on bony healing of cortical mandibular defects. An experimental study in minipigs // Clin. Oral Implants Res. 2004. V. 15, № 3. P. 301—307.
11. Ito K., Yamada Y., Naiki T., Ueda M. Simultaneous implant placement and bone regeneration around dental implants using tissue-engineered bone with fibrin glue, mesenchymal stem cells and platelet-rich plasma // Clin. Oral Implants Res. 2006. V. 17, № 5. P. 579—586.
12. Kaijzel E.L., Koolwijk P., Erck van M.G. et al. Molecular weight fibrinogen variants determine angiogenesis rate in a fibrin matrix in vitro and in vivo // J. Thromb. Haemost. 2006. V. 4, № 9. P. 1975—1981.
13. Kellouche S., Mourah S., Bonnefoy A. et al. Platelets, thrombospondin-1 and human dermal fibroblasts cooperate for stimulation of endothelial cell tubulogenesis through VEGF and PAI-1 regulation // Exp. Cell. Res. 2007. V. 313, № 3. P. 486—499.
14. Laidmae I., McCormick M.E., Herod J.L. et al. Stability, sterility, coagulation, and immunologic studies of salmon coag-ulation proteins with potential use for mammalian wound healing and cell engineering // Biomaterials. 2006. V. 27, № 34. P. 5771—5779.
15. London R.M., Roberts F.A., Baker D.A. et al. Histologic comparison of a thermal dual-etched implant surface to ma-chined, TPS, and HA surfaces: bone contact in vivo in rabbits // Int. J. Oral Maxillofac. Implants. 2002. V. 17, № 3. P. 369—376.
16. McDougall S., Dallon J., Sherratt J., Maini P. Fibroblast migration and collagen deposition during dermal wound healing: mathematical modelling and clinical implications // Philos Transact. A Math. Phys. Eng. Sci. 2006. V. 364, № 1843. P. 1385—1405.
17. Schmidt M.B., Chen E.H., Lynch S.E. A review of the effects of insulin-like growth factor and platelet derived growth factor on in vivo cartilage healing and repair // Osteoarthritis Cartilage. 2006. V. 14, № 5. P. 403—412.
18. Schwartz-Arad D., Levin L., Aba M. The use of platelet rich plasma (PRP) and platelet rich fibrin (PRP) extracts in dental implantology and oral surgery // Refuat Hapeh Vehashinayim. 2007. V. 24, № 1. P. 51—55, 84.
19. Spotnitz W.D., Prabhu R. Fibrin sealant tissue adhesive--review and update // J. Long Term Eff. Med. Implants. 2005. V. 15, № 3. P. 245—270.
20. Valbonesi M. Fibrin glues of human origin // Best Pract. Res. Clin. Haematol. 2006. V. 19, № 1. P. 191—203.
Review
For citations:
Maiborodin I.V., Sheplev B.V., Drovosekov M.N., Kolesnikov I.S., Toder M.S., Shevela А.A. The fibrin technologies in acceleration of damaged bone regeneration in experiment. Bulletin of Siberian Medicine. 2012;11(4):49-56. (In Russ.) https://doi.org/10.20538/1682-0363-2012-4-49-56