Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury
I. V. Tolmachev,
A. V. Anisin,
A. M. Bala,
D. A. Vrazhnov,
A. V. Shapovalov,
M. Yu. Kotlovskiy,
V. V. Laptev,
K. S. Brazovskiy https://doi.org/10.20538/1682-0363-2023-4-122-129
Abstract
The aim of this study was to apply integrative physiological mathematical models to simulate physiological parameters in traumatic shock caused by lower limb blast injury.
Materials and methods. At the first stage of mathematical modeling, we applied lumped parameter integrative physiological models, and at the second stage we used neural networks.
Results. We developed a clinical decision support system that allows to determine the intensity of blood loss in lower limb blast injuries according to physiological monitoring data.
Conclusion. The developed approaches make it possible to partially solve the problem associated with the impossibility of accumulating a sufficient amount of medical data for a specific person to create an adequate personalized clinical decision support system.
About the Authors
I. V. Tolmachev
Siberian State Medical University;
Federal Research Institute for Healthcare Organization and Informatization
Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050,
11, Dobrolyubova Str., Moscow, 127254
A. V. Anisin
S.M. Kirov Military Medical Academy
Russian Federation
Russian Federation
6, Academika Lebedeva Str., Saint Petersburg, 194044
A. M. Bala
S.M. Kirov Military Medical Academy
Russian Federation
Russian Federation
6, Academika Lebedeva Str., Saint Petersburg, 194044
D. A. Vrazhnov
Siberian State Medical University
Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050
A. V. Shapovalov
Siberian State Medical University
Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050
M. Yu. Kotlovskiy
Federal Research Institute for Healthcare Organization and Informatization
Russian Federation
Russian Federation
11, Dobrolyubova Str., Moscow, 127254
V. V. Laptev
National Research Tomsk Polytechnic University
Russian Federation
Russian Federation
30, Lenina Av., Tomsk, 634050
K. S. Brazovskiy
Siberian State Medical University;
National Research Tomsk Polytechnic University
Russian Federation
Russian Federation
2, Moscow Trakt, Tomsk, 634050,
30, Lenina Av., Tomsk, 634050
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Review
For citations:
Tolmachev I.V., Anisin A.V., Bala A.M., Vrazhnov D.A., Shapovalov A.V., Kotlovskiy M.Yu., Laptev V.V., Brazovskiy K.S. Mathematical modeling of physiological parameters in traumatic shock caused by lower limb blast injury. Bulletin of Siberian Medicine. 2023;22(4):122-129. https://doi.org/10.20538/1682-0363-2023-4-122-129
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