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REMODELING OF THE LEFT VENTRICLE: ONE OR SEVERAL SCENARIOS?

https://doi.org/10.20538/1682-0363-2016-4-120-139

Abstract

The authors of the review have analyzed papers published on the problem of remodeling of the left ventricle (LV), which is in accordance with a consensus paper from an International Forum on Cardiac Remodeling may be defined as genome expression, molecular, cellular and interstitial changes that are manifested clinically as changes in size, shape and function of the LV after cardiac injury. Remodeling of the LV is often seen as a nonspecific process independent of the nature of the underlying disease (cluster of disease). This approach, contrary to the theory of multimodal response of the myocardium (myocytes and interstitium) on the molecular-genetic, cellular, tissue, and organ levels, largely depending on the nature and duration of the triggering factor, as well as modern ideas about the types of LV remodeling and dividing the latter into serdechadaptive and non-adaptive forms, was the subject of legitimate criticism. Analyzed scenarios the molecular and cellular events, as well as deals with diagnosis of left ventricular remodeling. Discusses the classification of LV remodeling.

About the Authors

V. V. Kalyuzhin
Siberian State Medical University 2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation

MD, Professor of the Department of Hospital Therapy with a Сourse of Physical Rehabilitation and Sports Medicine, Siberian State Medical University, Tomsk, Russian Federation



A. T. Teplyakov
Research Institute of Cardiology 111а, Kievskaya St., 634012, Tomsk, Russian Federation
Russian Federation

MD, Professor, Head of the Department of Heart Failure, Research Institute for Cardiology, Tomsk, Russian Federation



M. A. Solovtsov
Regional Clinical Hospital 96, I. Chernuh St., Tomsk, 634063, Russian Federation
Russian Federation

Doctor of the Department of Ultrasonic Diagnostics, Regional Clinical Hospital, Tomsk, Russian Federation



E. V. Kalyuzhina
Siberian State Medical University 2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation

MD, Professor of the Department of Hospital Therapy with a Сourse of Physical Rehabilitation and Sports Medicine, Siberian State Medical University, Tomsk, Russian Federation



I. D. Bespalova
Siberian State Medical University 2, Moscow Trakt, Tomsk, 634050, Russian Federation
Russian Federation

PhD, Head of the Department of Social Work, Social and Clinical Psychology, Siberian State Medical University, Tomsk, Russian Federation



N. N. Terentyeva
Surgut State University 1, Lenina Av., Surgut, 628412, Russian Federation
Russian Federation

PhD, Associate Professor of the Department of Hospital Therapy, Surgut State University, Surgut, Russian Federation



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Kalyuzhin V.V., Teplyakov A.T., Solovtsov M.A., Kalyuzhina E.V., Bespalova I.D., Terentyeva N.N. REMODELING OF THE LEFT VENTRICLE: ONE OR SEVERAL SCENARIOS? Bulletin of Siberian Medicine. 2016;15(4):120-139. (In Russ.) https://doi.org/10.20538/1682-0363-2016-4-120-139

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