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DEVELOPMENT OF THE TECHNIQUE OF QUANTITATIVE DEFINITION OF TRIAZAVIRIN IN WATER SOLUTIONS WITH USE OF THE SPECTROPHOTOMETRY METHOD

https://doi.org/10.20538/1682-0363-2014-3-132-136

Abstract

Authors of article developed techniques of quantitative definition Triazavirin in water solutions with use of a method of a spectrophotometry. Three options of a method of a s spectrophotometry are used: direct spectrophotometry, spectrophotometry according to A.M. Firordt, a spectrophotometry with use of standard solution. For all techniques calculation of metrological characteristics is carried out. The developed techniques of quantitative definition were applicable for practical use in the pharmaceutical analysis. The relative error of quantitative definition Triazavirin in water solutions made 0.37%, 0.14% and 8.29% respectively for a direct spectrophotometry, a spectrophotometry with use of standard solution, a spectrophotometry according to A.M. Firordt.

About the Authors

M. Yu. Kinev
Ural State Medical University, Yekaterinburg; JSC “Ural`s Centrum of biofarmaceutical technology”, Yekaterinburg
Russian Federation
Kinev Mikhail Yu. 


O. A. Melnikova
Ural State Medical University, Yekaterinburg; JSC “Ural`s Centrum of biofarmaceutical technology”, Yekaterinburg
Russian Federation
Melnikova Olga A.


A. Yu. Petro
Ural State Medical University, Yekaterinburg; JSC “Ural`s Centrum of biofarmaceutical technology”, Yekaterinburg
Russian Federation
Petrov Aleksanr Yu.


D. V. Zaboyarkina
Ural State Medical University, Yekaterinburg; JSC “Ural`s Centrum of biofarmaceutical technology”, Yekaterinburg
Russian Federation
Zaboyarkina Dar’ya V.


References

1. Blinnikova A.A. Spektrofotometriya and photoelectrocolorimetry in the analysis of medicines: Manual. Tomsk, 2005. 96 p. (in Russian).

2. Dubkova N.S., Melnikov O.A., Petrov A.Yu. Studying of intermolecular interaction in system триазавирин – lemon acid spektrofotometrichesky the method. Messenger of a magistracy, 2013, no. 2 (17), pp. 4–6 (in Russian).


Review

For citations:


Kinev M.Yu., Melnikova O.A., Petro A.Yu., Zaboyarkina D.V. DEVELOPMENT OF THE TECHNIQUE OF QUANTITATIVE DEFINITION OF TRIAZAVIRIN IN WATER SOLUTIONS WITH USE OF THE SPECTROPHOTOMETRY METHOD. Bulletin of Siberian Medicine. 2014;13(3):132-136. (In Russ.) https://doi.org/10.20538/1682-0363-2014-3-132-136

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)