Plasma concentrations of endothelial nitric oxide synthase (enos) after different physical exercises
https://doi.org/10.20538/1682-0363-2017-1-20-26
Abstract
The purpose of the study is to evaluate the effect of dynamic and static exercises on eNOS concentrations in the blood plasma of athletes who do cyclic and strength kind of sports, as well as in men, who are not involved in any sports.
Materials and methods. Determination of plasma concentrations of eNOS was performed by using enzyme immunoassay. Blood samples were collected from weightlifters and track and field athletes before and after static and dynamic exercises.
Results. It has been shown that regular exercises contribute to a significant increase in the background level of endothelial nitric oxide synthase (eNOS) in the plasma of athletes. It is necessary to note that eNOS is almost twice higher in the weightlifters than in the track and field athletes. eNOS concentrations significantly decrease in athletes after static exercises , but on the contrary, increase after dynamic exercises. eNOS level rise in untrained individuals occurs after all kinds of exercises, although the influence of dynamic exercises is much more pronounced. Plasma concentrations of eNOS in all groups returned to baseline during the recovery period.
These results suggest that the underlying mechanism that regulates the amount of eNOS in the plasma during exercises is associated with vascular factors, first and foremost, with the intensity of regional blood flow and its impact on the endothelium surface. Therefore, this protein cannot be positioned as a representative of a myokine group.
About the Authors
E. Yu. Dyakova
National Research Tomsk State University (NR TSU)
Russian Federation
Russian Federation
DM, Associate Professor of the Department of Sport and Wellness Outdoor Tourism, and Sports Physiology and Medicine,
36, Lenina Str., Tomsk, 634050
L. V. Kapilevich
National Research Tomsk State University (NR TSU);
National Research Tomsk Polytechnic University (NR TPU)
Russian Federation
Russian Federation
DM, Head of the Department of Sport and Wellness Outdoor Tourism, and Sports Physiology and Medicine, 36, Lenina Str., Tomsk, 634050;
Professor, Department of Sports Disciplines, 30, Lenina Str., Tomsk, 634050
A. N. Zaharova
National Research Tomsk State University (NR TSU)
Russian Federation
Russian Federation
Graduate Student, Department of Sport and Wellness Outdoor Tourism, and Sports Physiology and Medicine,
36, Lenina Str., Tomsk, 634050
A. V. Kabachkova
National Research Tomsk State University (NR TSU)
Russian Federation
Russian Federation
PhD, Associate Professor of the Department of Sport and Wellness Outdoor Tourism, and Sports Physiology and Medicine,
36, Lenina Str., Tomsk, 634050
T. A. Kironenko
National Research Tomsk State University (NR TSU)
Russian Federation
Russian Federation
Graduate Student, Department of Sport and Wellness Outdoor Tourism, and Sports Physiology and Medicine,
36, Lenina Str., Tomsk, 634050
S. N. Orlov
National Research Tomsk State University (NR TSU);
Lomonosov Moscow State University;
Research Centre, Centre Hospitalier de l’Université de Montréal
Canada
Canada
Professor of the Department of Sport and Wellness Outdoor Tourism, and Sports Physiology and Medicine National Research Tomsk State University, 36, Lenina Str., Tomsk, 634050;
DM, Head of the Laboratory of Physical Chemistry of Biological Membranes, Faculty of Biology, Moscow State University, 1, Leninskiye Goru, Moscow, 119991;
Professor of the Emeritus Faculty of Medicine University of Montreal, Montreal
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Review
For citations:
Dyakova E.Yu., Kapilevich L.V., Zaharova A.N., Kabachkova A.V., Kironenko T.A., Orlov S.N. Plasma concentrations of endothelial nitric oxide synthase (enos) after different physical exercises. Bulletin of Siberian Medicine. 2017;16(1):20-26. (In Russ.) https://doi.org/10.20538/1682-0363-2017-1-20-26
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