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Efficacy of GLP-1 analog to achieve metabolic control and correction of body weight in patients with type 2 diabetes mellitus

https://doi.org/10.20538/1682-0363-2011-6-114-119

Abstract

Obesity associated with the enhanced risk of cardiovascular disorders plays a key role in the evolvement and progression of type 2 diabetes mellitus (DM2). Incretin mimetics are the sole class of hypoglycemic agents that not only effectively correct hyperglycemia but also reduce body weight. Exenatide (Byetta, Eli Lilly, USA) is the first drug of this class approved for the use as monotherapy. This paper presents data of clinical studies and owns data on the effectiveness of the drug Byetta in achieving metabolic control and weight correction in patients with type 2 diabetes.

About the Authors

T. V. Saprina
Сибирский государственный медицинский университет
Russian Federation


T. K. Gudkova
Сибирский государственный медицинский университет
Russian Federation


V. A. Stolyarova
Сибирский государственный медицинский университет
Russian Federation


S. Yu. Martynova
Сибирский государственный медицинский университет
Russian Federation


N. G. Dudarkova
Сибирский государственный медицинский университет
Russian Federation


T. G. Yaroshevskaya
Сибирский государственный медицинский университет
Russian Federation


Yu. A. Kabirova
Сибирский государственный медицинский университет
Russian Federation


O. A. Pavlenko
Сибирский государственный медицинский университет
Russian Federation


I. N. Vorozhtsova
Сибирский государственный медицинский университет
Russian Federation


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Review

For citations:


Saprina T.V., Gudkova T.K., Stolyarova V.A., Martynova S.Yu., Dudarkova N.G., Yaroshevskaya T.G., Kabirova Yu.A., Pavlenko O.A., Vorozhtsova I.N. Efficacy of GLP-1 analog to achieve metabolic control and correction of body weight in patients with type 2 diabetes mellitus. Bulletin of Siberian Medicine. 2011;10(6):114-119. (In Russ.) https://doi.org/10.20538/1682-0363-2011-6-114-119

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)