Opistorchis felineus invasion influence on immunity in bronchial asthma
https://doi.org/10.20538/1682-0363-2010-3-85-90
Abstract
To investigate the molecular mechanisms of human immune response modification by Opisthorchis felineus antigens in bronchial asthma. The experimental study was performed with cell cultures from patients with bronchial asthma, patients with opisthorchiasis, and patients with BA and opisthorchiasis co-occurred. A proposed down-regulation of immune response by higher level of IL10 and TGFB genes expression in patients with opisthorchiasis was revealed.
About the Authors
L. M. Ogorodova
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
M. B. Freidin
НИИ медицинской генетики СО РАМН
Russian Federation
Russian Federation
A. E. Sazonov
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
O. S. Fyodorova
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
I. A. Deyev
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
Ye. E. Kremer
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
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Review
For citations:
Ogorodova L.M., Freidin M.B., Sazonov A.E., Fyodorova O.S., Deyev I.A., Kremer Ye.E. Opistorchis felineus invasion influence on immunity in bronchial asthma. Bulletin of Siberian Medicine. 2010;9(3):85-90. (In Russ.) https://doi.org/10.20538/1682-0363-2010-3-85-90
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