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Role of cytoskeleton in formation of airway muscle activity in the presence of nanosized magnetite

https://doi.org/10.20538/1682-0363-2010-6-41-43

Abstract

The mechanographic method was used to study the influence of iron oxide nano-powder on airway muscle activity in guinea pigs. Under the action of nanomaterial on isolated segments, amplitudes of cholinergic and histaminergic contractile reactions increased. The pre-processing of cytoskeleton by colchicines and nocodazole disintegrators led to an increase in the mechanical stress of segments under the action of carbacholine and histamine.

About the Authors

T. N. Zaitseva
Институт оптики атмосферы ТНЦ СО РАН
Russian Federation


A. V. Nosarev
Сибирский государственный медицинский университет
Russian Federation


Ye. Yu. Diyakova
Томский государственный университет
Russian Federation


L. V. Kapilevich
Сибирский государственный медицинский университет
Russian Federation


B. G. Ageyev
Институт оптики атмосферы ТНЦ СО РАН
Russian Federation


L. N. Ogorodova
Сибирский государственный медицинский университет
Russian Federation


A. A. Magayeva
ТНЦ СО РАН
Russian Federation


O. G. Terekhova
ТНЦ СО РАН
Russian Federation


V. I. Iteen
ТНЦ СО РАН
Russian Federation


References

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5. Koltsova S.V., Gusakova S.V., Anfinogenova Y.J. et al. Vascular smooth muscle contraction evoked by cell volume modulation: role of the cytoskeleton network //Cell. Physiol. Biochem. 2008. № 21. P. 29—36.


Review

For citations:


Zaitseva T.N., Nosarev A.V., Diyakova Ye.Yu., Kapilevich L.V., Ageyev B.G., Ogorodova L.N., Magayeva A.A., Terekhova O.G., Iteen V.I. Role of cytoskeleton in formation of airway muscle activity in the presence of nanosized magnetite. Bulletin of Siberian Medicine. 2010;9(6):41-43. (In Russ.) https://doi.org/10.20538/1682-0363-2010-6-41-43

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)