The characteristic of endothelium-dependent vasodilatation in athletes and untrained volunteers
https://doi.org/10.20538/1682-0363-2018-4-42-46
Abstract
It is shown that strength-training athletes and track and field athletes have endothelial dysfunction. The vascular endothelium activity is not related to the direction of physical exercises. At the same time, the dynamic physical exercise induces endothelium vasodilatation function in all groups. Apparently, it can be the adaptive response to regular high-intensity physical exercises. At the same time it is a risk factor for acute vascular disorders.
About the Authors
V. V. Kologrivova
National Research Tomsk State University (NR TSU)
Russian Federation
Russian Federation
Kologrivova Valeriya V., Postgraduate Student, Department of Sport Tourism, Sport Physiology and Medicine
36, Lenin Str., Tomsk, 634050
A. N. Zakharova
National Research Tomsk State University (NR TSU)
Russian Federation
Russian Federation
Zakharova A.N., Associate Professor, Department of Sport Tourism, Sport Physiology and Medicine
36, Lenin Str., Tomsk, 634050
E. V. Pakhomova
National Research Tomsk State University (NR TSU)
Russian Federation
Russian Federation
Pakhomova Elizaveta V., Student, Department of Sport Tourism, Sport Physiology and Medicine
36, Lenin Str., Tomsk, 634050
V. N. Vasilyev
Siberian State Medical University (SSMU)
Russian Federation
Russian Federation
Vasilyev Vladimir N., DBSc, Professor, Department of Physical Culture
2, Moscow Trakt, Tomsk, 634050
L. V. Kapilevich
National Research Tomsk State University (NR TSU);
National Research Tomsk Polytechnic University (NR TPU)
Russian Federation
Russian Federation
Kapilevich Leonid V., Head of the Department of Sport Tourism, Sport Physiology and Medicine, NR TSU; Head of the Department of Physical Culture, NR TPU
36, Lenin Str., Tomsk, 634050, 30, Lenin Str., Tomsk, 634050
References
1. Green D.J., Spence A., Rowley N., Thijssen D.H., Naylor L.H. Vascular adaptation in athletes: is there an athlete’s artery? Exp Physiol. 2012; 97 (3): 295–304. DOI: 10.1113/expphysiol.2011.058826
2. Laughlin M.H. Endothelium-mediated control of coronary vascular tone after chronic exercise training. Med. Sci. Sports. Exerc. 1995; 27 (8): 1135–1144.
3. Manson J.E., Hu F.B., Rich-Edwards J.W., Colditz G.A., Stampfer M.J., Willett W.C., Speizer F.E., Hennekens C.H. A prospective study of walking as compared with vigorous exercise in the prevention of coronary heart disease in women. N. Engl. J. Med. 1999; 341 (9): 650–658.
4. Paffenbarger R.S. Jr., Hyde R.T., Wing A.L., Hsieh C.C. Physical activity, all-cause mortality, and longevity of college alumni. N. Engl. J. Med. 1986; 314 (10): 605–613.
5. Paffenbarger R.S. Jr., Kampert J.B., Lee I.M., Hyde R.T., Leung R.W., Wing A.L. Changes in physical activity and other lifeway patterns influencing longevity. Med. Sci. Sports. Exerc. 1994; 26 (7): 857–865.
6. Blair S.N., Kohl H.W., Barlow C.E., Paffenbarger R.S. Jr., Gibbons L.W., Macera C.A. Changes in physical fitness and all-cause mortality A prospective study of healthy and unhealthy men. JAMA. 1995; 273: 1093–1099.
7. Lee D.C., Sui X., Artero E.G., Lee I.M., Church T.S., McAuley P.A., Stanford F.C., Kohl H.W., Blair S.N. Long-term effects of changes in cardiorespiratory fitness and body mass index on all-cause and cardiovascular disease mortality in men: the Aerobics Center Longitudinal Study. Circulation. 2011; 124 (23): 2483–2490. DOI: 10.1161/CIRCULATIONAHA.111.038422.
8. Montero D., Walther G., Diaz-Caсestro C., Pyke K.E., Padilla J. Microvascular dilator function in athletes: a systematic review and meta-analysis. Med. Sci. Sports Exerc. 2015; 47 (7): 1485–1494. DOI: 10.1249/MSS.0000000000000567.
9. Kosheleva N.Yа., Rebrova A.P. Endothelial dysfunction in patients with chronic heart failure. Vestnik sovremennoy klinicheskoy meditsiny. 2009; 2 (1): 9–14 (in Russ.)
10. Petrishchev N.N., Vasina L.V., Vlasov T.D., Gavrisheva N.A., Menshutina M.A. Typical forms of endothelial dysfunction. Kliniko-laboratornyy konsilium. 2007; 18: 31–35 (in Russ.)
11. Green D.J., Hopman M.T., Padilla J., Laughlin M.H., Thijssen D.H. Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli. Physiol. Rev. 2017; 97 (2): 495–528. DOI: 10.1152/physrev.00014.2016.
12. Hawley J.A., Hargreaves M., Joyner M.J., Zierath J.R. Integrative biology of exercise. Cell. 2014; 159 (4): 738– 749. DOI: 10.1016/j.cell.2014.10.029.
13. Laughlin M.H., Newcomer S.C., Bender S.B. Importance of hemodynamic forces as signals for exercise-induced changes in endothelial cell phenotype. J. Appl. Physiol. 2008; 104 (3): 588–600.
14. Dzau V.J., Gibbons G.H., Morishita R., Pratt R.E. New perspectives in hypertension research. Potentials of vascular biology. Hypertension. 1994; 23: 1132–1140.
15. D’yakova Ye.Yu., Kapilevich L.V., Zakharova A.N., Kabachkova A.V., Kironenko T.A., Orlov S.N. Endothelial synthase nitric oxide in the plasma after exercise of various kinds. Byulleten’ sibirskoy meditsiny – Bulletin Siberian Medicine. 2017; 16 (1): 20–26 (in Russ.)
16. Green D.J., Dawson E.A., Groenewoud H.M., Jones H., Thijssen D.H. Is flow-mediated dilation nitric oxide mediated?: A meta-analysis. Hypertension. 2014; 63 (2): 376– 382. DOI: 10.1161/HYPERTENSIONAHA.113.02044.
17. Mestek M.L., Westby C.M., van Guilder G.P., Greiner J.J., Stauffer B.L., de Souza C.A. Regular aerobic exercise, without weight loss, improves endothelium-dependent vasodilation in overweight and obese adults. Obesity. 2010; 18 (8): 1667–1669. DOI: 10.1038/oby.2009.467.
Review
For citations:
Kologrivova V.V., Zakharova A.N., Pakhomova E.V., Vasilyev V.N., Kapilevich L.V. The characteristic of endothelium-dependent vasodilatation in athletes and untrained volunteers. Bulletin of Siberian Medicine. 2018;17(4):42-46. https://doi.org/10.20538/1682-0363-2018-4-42-46
Views:
1271
Email this article 