Mesalazin-induced eosinophilic pneumonia in a 15-year-old boy with ulcerative colitis
G. N. Yankinа,
L. V. Gorlenko,
E. V. Loshkova,
E. I. Kondratyeva,
E. Yu. Tuteva,
A. A. Terenteva,
V. A. Zhelev,
E. V. Mikhalev,
T. A. Shemyakinа,
T. S. Krivonogova,
N. A. Ryzhakova,
E. V. Romanova https://doi.org/10.20538/1682-0363-2019-3-245-257
Abstract
One of the most difficult categories of patients is patients with inflammatory bowel disease. A clinical case of the development of mesalazine-induced eosinophilic pneumonia in a 15-year-old boy with ulcerative colitis is presented. The patient suffered an acute respiratory disease, which caused the aggravation of ulcerative colitis and, accordingly, an increase in the dose of mesalazine. Against this background, the child had active complaints of heaviness in the chest to the left. Eosinophilia was noted in the blood. Analysis of clinical symptoms, X-ray data, microscopic examination of the pleural fluid, the results of spiral computed tomography of the chest allowed a differential diagnosis of the main symptoms and associated identified pulmonary lesions with mesalazine.
About the Authors
G. N. Yankinа
Siberian State Medical University (SSMU);
Children’s Hospital № 1
Russian Federation
Russian Federation
DM, Professor, Department of Hospital Pediatrics, 2, Moscow Tract, Tomsk, 634050;
4, Moscow Tract, Tomsk, 634050
L. V. Gorlenko
Siberian State Medical University (SSMU);
Children’s Hospital № 1
Russian Federation
Russian Federation
PhD, Assistent Professor, Department of Hospital Pediatrics, 2, Moscow Tract, Tomsk, 634050;
4, Moscow Tract, Tomsk, 634050
E. V. Loshkova
Siberian State Medical University (SSMU);
Children’s Hospital № 1
Russian Federation
Russian Federation
PhD, Assistent Professor, Нead of Affective States Department, 2, Moscow Tract, Tomsk, 634050;
4, Moscow Tract, Tomsk, 634050
E. I. Kondratyeva
Siberian State Medical University (SSMU);
Medical Genetics Research Centre
Russian Federation
Russian Federation
DM, Professor, Department of Hospital Pediatrics, 2, Moscow Tract, Tomsk, 634050;
Head of the Scientific Advisory Department of Cystic Fibrosis, 1, Moskvorechye, Moscow, 115478
E. Yu. Tuteva
Siberian State Medical University (SSMU);
Children’s Hospital № 1
Russian Federation
Russian Federation
PhD, Assоciate Professor, Department of Hospital Pediatrics, 2, Moscow Tract, Tomsk, 634050;
4, Moscow Tract, Tomsk, 634050
A. A. Terenteva
Siberian State Medical University (SSMU)
Russian Federation
Russian Federation
PhD, Assоciate Professor, Department of Hospital Pediatrics,
2, Moscow Tract, Tomsk, 634050
V. A. Zhelev
Siberian State Medical University (SSMU)
Russian Federation
Russian Federation
DM, Professor, Head of the Department of Hospital Pediatrics,
2, Moscow Tract, Tomsk, 634050
E. V. Mikhalev
Siberian State Medical University (SSMU);
Children’s Hospital № 1
Russian Federation
Russian Federation
DM, Professor, Department of Hospital Pediatrics, 2, Moscow Tract, Tomsk, 634050;
4, Moscow Tract, Tomsk, 634050
T. A. Shemyakinа
Siberian State Medical University (SSMU)
Russian Federation
Russian Federation
PhD, Assоciate Professor, Department of Hospital Pediatrics,
2, Moscow Tract, Tomsk, 634050
T. S. Krivonogova
Siberian State Medical University (SSMU)
Russian Federation
Russian Federation
DM, Professor, Department of Hospital Pediatrics,
2, Moscow Tract, Tomsk, 634050
N. A. Ryzhakova
Siberian State Medical University (SSMU)
Russian Federation
Russian Federation
PhD, Assistent Professor, Department of Hospital Pediatrics,
2, Moscow Tract, Tomsk, 634050
E. V. Romanova
Siberian State Medical University (SSMU)
Russian Federation
Russian Federation
Senior Lecturer, Microbioiogy and Virology Division,
2, Moscow Tract, Tomsk, 634050
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Review
For citations:
Yankinа G.N., Gorlenko L.V., Loshkova E.V., Kondratyeva E.I., Tuteva E.Yu., Terenteva A.A., Zhelev V.A., Mikhalev E.V., Shemyakinа T.A., Krivonogova T.S., Ryzhakova N.A., Romanova E.V. Mesalazin-induced eosinophilic pneumonia in a 15-year-old boy with ulcerative colitis. Bulletin of Siberian Medicine. 2019;18(3):245-257. (In Russ.) https://doi.org/10.20538/1682-0363-2019-3-245-257
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