A case of anti-NMDA-receptor encephalitis presenting as febrile catatonia
https://doi.org/10.20538/1682-0363-2019-4-266-272
Abstract
We described a case of anti-NMDA-receptor encephalitis presenting as febrile catatonia in a 22-year-old patient with no somatic burden. We looked into the dynamics of the disease and treatment strategy. In the discussion, we provided analysis of the presented case, as well as issues related to research perspectives in this field.
About the Authors
A. B. Shmukler
Moscow Research Institute of Psychiatry – the Branch of V. Serbsky National Medical Research Centre (NMRC) for Psychiatry and Narcology
Russian Federation
Russian Federation
DM, Professor, Deputy Director for Research,
3/10, Poteshnaya Str., Moscow, 107076
A. A. Ivashkina
P.B. Gannushkin Moscow Psychiatric Hospital no. 4
Russian Federation
Russian Federation
Head of Psychiatric Department,
3, Poteshnaya Str., Moscow, 107076
A. A. Murashko
Moscow Research Institute of Psychiatry – the Branch of V. Serbsky National Medical Research Centre (NMRC) for Psychiatry and Narcology
Russian Federation
Russian Federation
Resident,
3/10, Poteshnaya Str., Moscow, 107076
References
1. Steiner J., Walter M., Glanz W., Sarnyai Z., Bernstein H.G., Vielhaber S., Kästner A., Skalej M., Jordan W., Schiltz K., Klingbeil C., Wandinger K.P., Bogerts B., Stoecker W. Increased prevalence of diverse N-methyl-D-aspartate glutamate receptor antibodies in patients with an initial diagnosis of schizophrenia: specific relevance of IgG NR1a antibodies for distinction from N-methyl-D-aspartate glutamate receptor encephalitis. JAMA Psychiatry. 2013; 70 (3): 271–278. DOI: 10.1001/2013.jamapsychiatry.86.
2. Vitaliani R., Mason W., Ances B., Zwerdling T., Jiang Z., Dalmau J. Paraneoplastic encephalitis, psychiatric symptoms, and hypoventilation in ovarian teratoma. Ann. Neurol. 2005; 58 (4): 594–604. DOI: 10.1002/ana.20614.
3. Dalmau J., Tüzün E., Wu H.Y., Masjuan J., Rossi J.E., Voloschin A., Baehring J.M., Shimazaki H., Koide R., King D., Mason W., Sansing L.H., Dichter M.A., Rosenfeld M.R., Lynch D.R. Paraneoplastic anti-N-methyl-D-aspartate receptor encephalitis associated with ovarian teratoma. Ann. Neurol. 2007; 61 (1): 25–36. DOI: 10.1002/ana.21050.
4. Al-Diwani A., Handel A., Townsend L., Pollak T., Leite M.I., Harrison P.J., Lennox B.R., Okai D., Manohar S.G., Irani S.R. The psychopathology of NMDAR-antibody encephalitis in adults: a systematic review and phenotypic analysis of individual patient data. Lancet Psychiatry. 2019; 6 (3): 235–246. DOI: 10.1016/S2215-0366(19)30001-X.
5. Barry H., Byrne S., Barrett E., Murphy K.C., Cotter D.R. Anti-N-methyl-d-aspartate receptor encephalitis: review of clinical presentation, diagnosis and treatment. BJPsych. Bull. 2015; 39 (1): 19–23. DOI: 10.1192/pb.bp.113.045518.
Review
For citations:
Shmukler A.B., Ivashkina A.A., Murashko A.A. A case of anti-NMDA-receptor encephalitis presenting as febrile catatonia. Bulletin of Siberian Medicine. 2019;18(4):266-272. (In Russ.) https://doi.org/10.20538/1682-0363-2019-4-266-272
Views:
1246
Email this article 