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SCHILDER’S DISEASE (CASE)

https://doi.org/10.20538/1682-0363-2013-5-133-138

Abstract

Schilder’s leukoencephalitis was described by American neurologist and psychiatrist P.F. Schilder (1886– 1940). At present the pathology is regarded as acute diffuse form of multiple sclerosis, and it is characterized by demyelination of the brain. Clinical manifestations of pathological process varied. The disease is a rare, usually in children and adolescents. In patients older than 40 years of death can occur in a period of 6 months to 3 years from the onset of the first symptoms. Considering the rarity of the disease, we present a clinical case with autopsy data from our practice. 

About the Authors

V. M. Alifirova
Siberian State Medical University, Tomsk
Russian Federation
Alifirova Valentina M. 


T. A. Valikova
Siberian State Medical University, Tomsk
Russian Federation
Valikova Tatiyana A.


T. N. Nikolaeva
Siberian State Medical University, Tomsk
Russian Federation
Nikolaeva Tatiyana N.


N. V. Pugachenko
Siberian State Medical University, Tomsk
Russian Federation
Pugachenko Nataliya V


S. V. Vtorushin
Siberian State Medical University, Tomsk
Russian Federation
Vtorushin Sergei V.


References

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2. Popp А. John, Deshaie Eric М. Guide neurology: translation from English. Ed. N.N. Yakhno. Moscow., 2012. 688 p. (in Russian).

3. Lublin F.D., Rengold S.C. Defining The clinical course of multiple sclerosis: recults of an international survey. National Multiple Sclerosis Society (USA) Advisory Cjmmittee on Clinical Trials of new Agents in Multiple Sclerosis. Neurology, 1996, no. 46 (4), pp. 907–911.

4. Bembeyeva R.Ts., Serikov S.V., Pronin I.N., Korshunov A.G. Journal of Neuropathology and Psychiatry named after S.S. Korsakov, 2007, no. 1, pp. 63–67 (in Russian).

5. Scott W. Magnetic Resonance Imaging of the Brain and Spine. Atlas. 3rd ed. Philadelphia. Lippincott Williams & Wilkins, 2002.


Review

For citations:


Alifirova V.M., Valikova T.A., Nikolaeva T.N., Pugachenko N.V., Vtorushin S.V. SCHILDER’S DISEASE (CASE). Bulletin of Siberian Medicine. 2013;12(5):133-138. (In Russ.) https://doi.org/10.20538/1682-0363-2013-5-133-138

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)