Lipid-laden alveolar macrophages in induced sputum in patients with gastroesophageal reflux disease
https://doi.org/10.20538/1682-0363-2006-4-136-139
Abstract
The aim of the study was to evaluate the diagnostic role of a lipid index of macrophages in induced sputum as a marker of aspiration of acidic gastric contents. 17 patients with the diagnosis of gastroesophageal reflux disease (GERD) and 10 healthy volunteers without any chronic digestive disorder were examined. In the group of patients with GERD, the maximal number of cells with positive reaction to lipids (31,70 ± 17,55) and maximal lipid index (45,06 ± 17,15), exceeding the control value five times, were found ( р < 0,05). The detection of lipid-laden alveolar macrophages in induced sputum can become a screenings method for diagnostics of gastroesophageal reflux. This requires the further investigations to clear up its causes.
About the Authors
L. I. Volkova
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
O. A. Anichkina
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
I. V. Sukhodolo
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
R. I. Pleshko
Сибирский государственный медицинский университет
Russian Federation
Russian Federation
V. S. Bogomyagkov
Городская больница № 3
Russian Federation
Russian Federation
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Review
For citations:
Volkova L.I., Anichkina O.A., Sukhodolo I.V., Pleshko R.I., Bogomyagkov V.S. Lipid-laden alveolar macrophages in induced sputum in patients with gastroesophageal reflux disease. Bulletin of Siberian Medicine. 2006;5(4):136-139. (In Russ.) https://doi.org/10.20538/1682-0363-2006-4-136-139
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