THE FUNCTIONAL STATUS OF THE BILIARY SYSTEM AND LITHOGENECITY OF BILE IN PATIENTS WITH THE INFLAMMATORY BOWEL DISEASES
https://doi.org/10.20538/1682-0363-2013-6-112-119
Abstract
The task of this research was a study of the functional state of the biliary system and gallbladder bile composion in patients with the inflammatory bowel diseases (ulcerous colitis and Crohn 's disease).
Summary: The results showed a reduction in motor activity of the biliary tract and an increase the lithogenicity of the gallbladder bile in patients with average and severe degree of severity of ulcerative colitis and with Crohn's disease. All this can increased the risk of gallstone formation in these patients
About the Authors
A. A. MarkidonovaRussian Federation
Markidonova Anastasiya A.
E. I. Beloborodova
Russian Federation
Beloborodova Elvira I.
V. A. Burkovskaya
Russian Federation
Burkovskaya Vera A.
References
1. Rybak V.S., Il'ichenko L.Ju., Rumjancev V.G. Experimental and clinical gastroenterology, 2003, no. 1, pp. 47–50 (in Russian).
2. Krylov A.A., Kozlovich I.V., Stolov S.V. Extra-intestinal manifestations of ulcerative colitis. J. Therapeutic archives, 1993, vol. 65, no. 2, pp. 80–81 (in Russian).
3. Adler G. Crohn's disease and ulcerous colitis: a translation from German by A.A. Sheptulina. Moscow, G-MED Publ., 2001. 500 p. (in Russian).
4. Keulemans Y.S., Mok K.S., Slors J.F., Brink M.A., Gouma D.G., Tytgat G.N., Groen A.K. Concanavalin A-binding cholesterol crystallization inhibiting and promoting activity in bie from patients with Crohn’s disease compared to paitients with ulcerative colitis. Hepatol., 1999, Oct. 31 (4), pp. 685–691.
5. Damiao F.J., Sipahi A.M., Vezozzo D.P., Goncalves P.L., Fukui P., Laudanna A.A. Gallbladder hypokinesia in Crohn’s disease. Digestion, 1997, 58 (5), pp. 458–463.
6. Belousova E.A. Ulcerous colitis and Crohn's disease. Tver', Triada Publ., 2002. 129 p. (in Russian).
7. Halif I.L. Treatment strategy for ulcerous colitis. Russ. J. of Gastrent., Hepatol. and Coloproctology, 2006, no. 3, pp. 58– 61.
8. Halif I.L., Loranskaja I.D. Inflammatory bowel diseases (ulcerous colitis and Crohn's disease): clinic, diagnosis, treatment. Moscow, 2004. 88 p. (in Russian).
9. Best W.R., Becktel J.M., Singleton J.W. et al. Development of Crohn’s disease activity index. National Cooperative Crohn’s disease Study. Gastroenterology, 1976, vol. 70, pp. 439–444.
10. Maksimov V.A., Chernyshov A.L., Tarasov K.M. Duodenal study. Moscow, Medical Newspaper Publ., 1998. 193 p. (in Russian).
11. Maksimov V.A., Chernyshev A.L., Tarasov K.M., Neronov V.A. Biliary insufficiency. Moscow, Adamant Publ., 2008. 232 p. (in Russian).
12. Miroshnichenko V.P., Gajdaj V.N. Bile acids and cholesterol in bile in the bile duct disorders. J. Medical Business, 1984, no. 7, pp. 27–29 (in Russian).
13. Tilichenko Ju.A., Kapilevich N.A., Beloborodova Je.I. and other. Methods for determining the concentration of total lipid and phosphorus of bile. Lab. Business, 1990, no. 2, pp. 8–10 (in Russian).
14. Thomas P.J., Hofmann A.F. A simple calculation of the lithogenic index og bile: Expressing biliary lipid composition on rectangular coordinates. Gastrent, 1973, vol. 65, no. 4, pp. 698–700.
15. Rubens Ju.P., Jurika Je.V., Seleznev Ju.V. Indices lithogenicity bile: methods determining clinical accessibility, information content. J. Clinical Medicine, 1992, vol. 70, no. 7–8, pp. 39–41 (in Russian).
16. Swell L., Bell C.C., Gregory D.H. The cholesterol saturation index of human bile. Amer. J. Dig. Dis., 1974, vol. 19, no. 3, pp. 261–265.
17. Zubovskij G.A., Hmelevskaja N.M. Ultrasound scanning of the liver during preventive examinations. Med. Radiology, 1986, no. 5, pp. 20–25 (in Russian).
18. Weill F.S. Ultrasonography of digestive diseases. Second edition. St. Louis – Toronto – London. The C.V. Mosby Co.
19. Lapidus A., Akerlund J.E., Einarsson C. Gallbladder bile composition in patients with Crohn's disease. World J. Gastroenterol., 2006, Jan 7, 12(1), pp. 70–4, Centre of Gastrointestinal Disease, Ersta Hospital, Stockholm, Sweden.
Review
For citations:
Markidonova A.A., Beloborodova E.I., Burkovskaya V.A. THE FUNCTIONAL STATUS OF THE BILIARY SYSTEM AND LITHOGENECITY OF BILE IN PATIENTS WITH THE INFLAMMATORY BOWEL DISEASES. Bulletin of Siberian Medicine. 2013;12(6):112-119. (In Russ.) https://doi.org/10.20538/1682-0363-2013-6-112-119