IMMUNOLOGIC RISK FACTORS OF DEVELOPMENT OTITIS MEDIA WITH EFFUSION IN CHILDREN SUFFERING FROM CHRONIC ADENOIDITIS
https://doi.org/10.20538/1682-0363-2013-3-92-96
Abstract
There were 24 patients with chronic adenoiditis in the 1st group, another 24 patients with chronic adenoiditis in association with otitis media effusion (OME) were included in the 2d group. The study of mucosal immunity included assessment of SIgA, IL-6, IFN- and IL-10 levels in nasal washes. Decrease of SIgA content and increase of the number of IFN-γ-positive samples was revealed in children from the 2nd clinical group, which allows to regard these characteristics of the mucosal immunity as the risk factors for the development of otitis media with effusion.
About the Authors
N. V. Scherbik
Siberian State Medical University, Tomsk
Russian Federation
Scherbik Natal’ya V.
Russian Federation
Scherbik Natal’ya V.
A. V. Klimov
Siberian State Medical University, Tomsk
Russian Federation
Klimov Andrei V.
Russian Federation
Klimov Andrei V.
Ye. N. Kologrivova
Siberian State Medical University, Tomsk
Russian Federation
Kologrivova Yelena N.
Russian Federation
Kologrivova Yelena N.
O. V. Fyodorova
Siberian State Medical University, Tomsk
Russian Federation
Fyodorova Olga V.
Russian Federation
Fyodorova Olga V.
S. V. Komarova
Siberian State Medical University, Tomsk
Russian Federation
Komarova Svetlana V.
Russian Federation
Komarova Svetlana V.
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Review
For citations:
Scherbik N.V., Klimov A.V., Kologrivova Ye.N., Fyodorova O.V., Komarova S.V. IMMUNOLOGIC RISK FACTORS OF DEVELOPMENT OTITIS MEDIA WITH EFFUSION IN CHILDREN SUFFERING FROM CHRONIC ADENOIDITIS. Bulletin of Siberian Medicine. 2013;12(3):92-96. (In Russ.) https://doi.org/10.20538/1682-0363-2013-3-92-96
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