FEATURES KALLIKREIN-KININ SYSTEMS AND DYSFUNCTIONS ENDOTHELIUM AT NEWBORNS WITH HYPOXEMIC DEFEAT OF THE CENTRAL NERVOUS SYSTEM
https://doi.org/10.20538/1682-0363-2013-3-106-110
Abstract
Proteolytic systems of tissue and blood plasma take part in the processes of adaptation and protection of an organism, as well as in development of pathological reactions. 201 prematurely newborn of various degree gestation with hypoxemic affection of the central nervous system were under observation. We have studied the activity of kallikrein, kallikreinogen in newborns with hypoxic-ischemic encephalopathy. The activity of the kallikrein-kinin system was increased in all the groups against the background of the decreased inhibitory activity of blood plasma of different intensity, which can be used for the prediction of the course of diseases.
About the Authors
V. A. Zhelev
Siberian State Medical University, Tomsk
Russian Federation
Zhelev Victor A.
Russian Federation
Zhelev Victor A.
A. S. Pogudina
Siberian State Medical University, Tomsk
Russian Federation
Pogudina Anna S. - Ph.
Russian Federation
Pogudina Anna S. - Ph.
V. V. Gorev
Siberian State Medical University, Tomsk
Russian Federation
Gorev Valeriy V.
Russian Federation
Gorev Valeriy V.
References
1. Antonov A.G., Burkhova A., Baibarina Ye.N. Pediatrics, 2008, no. 5, pp. 39–42 (in Russian).
2. Veremeyenko K.N. Medical Business, 2004, no. 1, pp. 8–13 (in Russian).
3. Volodin N.N., Medvedev M.I., Suvorova N.D. Russian Herald of Perinatology and Pediatrics, 2002, no. 2, pp. 13–16 (in Russian).
4. Volodin N.N., Petrukhin А.С. Classification of perinatal lesions of the nervous system of the newborn: a practical guide. Moscow, 1999. 34 p. (in Russian).
5. Gomazkov O.A. Pathological Physiology and Experimental Therapy, 2007, no. 1, pp. 70–76 (in Russian).
6. Lupinskaya Z.A., Malakhov V.A., Belous A.M., Pasyura I.N., Doroshenko G.I. Cell-membrane aspects of pathogenesis, treatment and prevention of blood flow chronic cerebral ischemia and neurodegenerative processes. Kharkov, Ranok Publ., 2000. 172 p. (in Russian).
7. Ostroumova O.D., Dubinskaya R.E. Cardiology, 2010, no. 2, pp. 59–62 (in Russian).
8. Palchik A.B., Chupreyev I.V. Pediatrics, 2005, no. 3, pp. 11–14 (in Russian).
9. Surovikina M. Doctor, 2005, no. 3, pp. 7–10 (in Russian).
10. Chuvakova T.K. Neurochemical violations during hypoxic ischemic encephalopathy in premature infants. 2009. Available at: http://www.aiha.com (in Russian).
11. Szymonowicz W., Yu V.Y., Bajuk B. Neurodevelopmental outcome off periventricular hemorrhage and leucomalacia in infans 1250g or less at birth. J. Astbury Early Hum. Dev., 2000, vol. 14, no. 1, pp. 1–7.
12. Williams С.E., Mallard C., Tan W., Gluckman P.D. Pathophysiology of perinatal asphyxia. Clin. Perinatol., 2003, vol. 20, no. 2, pp. 305–325. 239.
Review
For citations:
Zhelev V.A., Pogudina A.S., Gorev V.V. FEATURES KALLIKREIN-KININ SYSTEMS AND DYSFUNCTIONS ENDOTHELIUM AT NEWBORNS WITH HYPOXEMIC DEFEAT OF THE CENTRAL NERVOUS SYSTEM. Bulletin of Siberian Medicine. 2013;12(3):106-110. (In Russ.) https://doi.org/10.20538/1682-0363-2013-3-106-110
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