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The results of epidemiological effectiveness study of Jodantipyrin as a drug for immediate prophylaxis of tick-borne encephalitis

https://doi.org/10.20538/1682-0363-2008-5-2-461-464

Abstract

Jodantipyrin is an antiviral medicament, inductor of endogenous interferon. It relates to the group of nonsteroidal antiinflammatory medicaments of pyrazolone derivative. The principal mechanism of Jodantipyrin antiviral effect is its ability to induce endogenous interferons of the 1 st and 2 nd types, what has been confirmed by the results of numerous and detailed preclinical and clinical trials. At the present time a long-term experience of this medicament application as a prophylactic agent in case of tick-borne encephalitis and data of postmarketing monitoring of the medicament safety have been accumulated. This experience confirms efficacy of the medicament in prophylaxis of tick-borne encephalitis.

About the Authors

V. N. Khudolei
ООО «НТМ»
Russian Federation


Ye. V. Zamyatina
ООО «НТМ»
Russian Federation


Ye. A. Kropotkina
ООО «НТМ»
Russian Federation


L. V. Lukashova
Сибирский государственный медицинский университет
Russian Federation


A. V. Lepyokhin
Сибирский государственный медицинский университет
Russian Federation


G. A. Danchinova
НЦ медицинской экологии ВСНЦ СО РАМН; Иркутский государственный медицинский университет
Russian Federation


V. I. Zlobin
НИИ вирусологии им. Д.И. Ивановского РАМН
Russian Federation


Review

For citations:


Khudolei V.N., Zamyatina Ye.V., Kropotkina Ye.A., Lukashova L.V., Lepyokhin A.V., Danchinova G.A., Zlobin V.I. The results of epidemiological effectiveness study of Jodantipyrin as a drug for immediate prophylaxis of tick-borne encephalitis. Bulletin of Siberian Medicine. 2008;7(5-2):461-464. (In Russ.) https://doi.org/10.20538/1682-0363-2008-5-2-461-464

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ISSN 1682-0363 (Print)
ISSN 1819-3684 (Online)