Modern methods for studying atherosclerosis and coronary artery disease: flow cytometry
https://doi.org/10.20538/1682-0363-2021-2-184-190
Abstract
The problem of atherosclerosis, which forms the pathological basis of coronary artery disease (CAD), is one of the most discussed ones in development of cardiovascular diseases. This chronic inflammatory disease involves interactions between different cells, and an atherosclerotic plaque is a complex immunological environment. Modern quantitative methods increase the understanding of the pathophysiological processes responsible for progression of atherosclerotic plaques. Flow cytometry is a powerful modern method that allows for a complex and simultaneous cell analysis. This review is devoted to studies on atherosclerosis and CAD performed using flow cytometry.
Supporting agencies: This study was conducted within the budgetary theme on the state assignment No. АААА-А17-117112850280-2 and within the grant from the Russian Foundation for Basic Research No. 19-015- 00055.
About the Authors
E. M. Stakhneva
Research Institute of Internal and Preventive Medicine (RIIPM) – Branch of the Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences (Branch of ICG SB RAS)
Russian Federation
Russian Federation
175/1, Bogatkova Str., Novosibirsk, 630089, Russian Federation
Yu. I. Ragino
Research Institute of Internal and Preventive Medicine (RIIPM) – Branch of the Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences (Branch of ICG SB RAS)
Russian Federation
Russian Federation
175/1, Bogatkova Str., Novosibirsk, 630089, Russian Federation
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Review
For citations:
Stakhneva E.M., Ragino Yu.I. Modern methods for studying atherosclerosis and coronary artery disease: flow cytometry. Bulletin of Siberian Medicine. 2021;20(2):184-190. https://doi.org/10.20538/1682-0363-2021-2-184-190
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