Modern Ideas about the Mechanisms of Intermittent hypoxia – hyperoxia training and the possibility of its use in cardiovascular diseases (literature review)
https://doi.org/10.20538/1682-0363-2025-2-162-168
Abstract
Intermittent hypoxia – hyperoxia therapy with individually dosed gas levels (ReOxy therapy) is a modification of the long-known method of intermittent normobaric hypoxia training. Currently, ReOxy therapy can be considered as an addition to physical training in programs of cardiological rehabilitation, primary and secondary prevention of a wide range of cardiovascular diseases, as well as an alternative to physical exercises if it is impossible to perform them.
This review examines the pathogenetic rationale, differences from traditional intermittent hypoxia training, and clinical prospects for the use of intermittent hypoxia – hyperoxia therapy in cardiovascular diseases.
Supporting agencies: The study was performed within the basic research topic of Research Institute for Complex Problems of Cardiovascular Diseases No. 0419-2022-0002.
About the Authors
N. B. Lebedeva
Research Institute for Complex Problems of Cardiovascular Diseases
Russian Federation
Competing Interests:
Russian Federation
6 Akademika L.S. Barbarasha Blvd., 650002 Kemerovo, Russian Federation
Competing Interests:
The authors declare the absence of obvious or potential conflict of interest related to the publication of this article.
A. P. Egle
Kuzbass Clinical Cardiology Dispensary named after Academician L.S. Barbarash
Russian Federation
Competing Interests:
Russian Federation
6 Akademika L.S. Barbarasha Blvd., 650002 Kemerovo, Russian Federation
Competing Interests:
The authors declare the absence of obvious or potential conflict of interest related to the publication of this article.
A. Yu. Sacharchuk
Research Institute for Complex Problems of Cardiovascular Diseases
Russian Federation
Competing Interests:
Russian Federation
6 Akademika L.S. Barbarasha Blvd., 650002 Kemerovo, Russian Federation
Competing Interests:
The authors declare the absence of obvious or potential conflict of interest related to the publication of this article.
Yu. A. Argunova
Research Institute for Complex Problems of Cardiovascular Diseases
Russian Federation
Competing Interests:
Russian Federation
6 Akademika L.S. Barbarasha Blvd., 650002 Kemerovo, Russian Federation
Competing Interests:
The authors declare the absence of obvious or potential conflict of interest related to the publication of this article.
O. L. Barbarash
Research Institute for Complex Problems of Cardiovascular Diseases
Russian Federation
Competing Interests:
Russian Federation
6 Akademika L.S. Barbarasha Blvd., 650002 Kemerovo, Russian Federation
Competing Interests:
The authors declare the absence of obvious or potential conflict of interest related to the publication of this article.
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Review
For citations:
Lebedeva N.B., Egle A.P., Sacharchuk A.Yu., Argunova Yu.A., Barbarash O.L. Modern Ideas about the Mechanisms of Intermittent hypoxia – hyperoxia training and the possibility of its use in cardiovascular diseases (literature review). Bulletin of Siberian Medicine. 2025;24(2):162-168. (In Russ.) https://doi.org/10.20538/1682-0363-2025-2-162-168
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