The possibilities of magnetic-resonance imaging in the evaluation of the hands in patients with juvenile idiopathic arthritis

To establish the informativeness of MRI in detecting lesions in patients with intra-articular structures of juvenile idiopathic arthritis was performed MRI and radiography of hands six patients (11 hands) at the age of 10 to 17 years old (the average length of illness (42.0 ± 20.5) months)

A wide range of changes in bone and soft tissue structures, including synovitis, bone erosion, tenosinovitis, bone marrow edema revealed. The advantage of MRI compared with radiography identified erosions in the amount of different localization. The proliferation of established synovitis, compared with the MRI data of clinical and laboratory parameters of inflammatory activity widespread. The data obtained from MRI can be used for diagnosis, prognosis and monitoring response to treatment, including early stage disease.

1. Benton N., Stewart N., Crabbe J. et al. MRI of the wrist in early rheumatoid arthritis can be used to predict functional outcome at 6 years // Ann. Rheum. Dis. 2004. № 63. Р. 555—561.

2. Boutry N., Larde A., Lapegue F. et al. Magnetic resonance imaging appearance of the hands and feet in patients with early rheumatoid arthritis // J. Rheumatol. 2003. № 30. Р. 671—679.

3. Conaghan P..G, O'Connor P., McGonagle D. et al. Elucidation of the relationship between synovitis and bone damage: a randomized magnetic resonance imaging study of individual joints in patients with early rheumatoid arthritis // Arthritis Rheum. 2003. № 48. Р. 64—71. doi: 10.1002/art.10747.

4. Van der Heijde D.M., van Leeuwen M.A., van Riel P.L. et al. Radiographic progression on radiographs of hands and feet during the first 3 years of rheumatoid arthritis measured according to Sharp's method (van der Heijde modification) // J. Rheumatol. 1995. № 22. Р. 1792—1796.

5. Hermann K.G., Backhaus M., Schneider U. et al. Rheuma-toid arthritis of the shoulder joint: comparison of conventional radiography, ultrasound, and dynamic contrast-enhanced magnetic resonance imaging // Arthritis Rheum. 2003. № 48. Р. 3338—3349. doi: 10.1002/art.11349.

6. Jimenez-Boj E., Nцbauer-Huhmann I., Hanslik-Schnabel B. et al. Bone erosions and bone marrow edema as defined by magnetic resonance imaging reflect true bone marrow in-flammation in rheumatoid arthritis // Arthritis Rheum. 2007. № 56 (4). Р. 1118—1124.

7. Klarlund M., Ostergaard M., Jensen K.E. et al. Magnetic resonance imaging, radiography, and scintigraphy of the finger joints: one year follow up of patients with early arthritis // The TIRA Group. Ann. Rheum. Dis. 2000. № 59. Р. 521—528.

8. Konig H., Sieper J., Wolf K.J. Rheumatoid arthritis: evalua-tion of hypervascular and fibrous pannus with dynamic MR imaging enhanced with Gd-DTPA // Radiology. 1990. № 176. Р. 473—477.

9. Lindegaard H.M., Vallo J., Horslev-Petersen K. et al. Low-cost, low-field dedicated extremity magnetic resonance ima¬ging in early rheumatoid arthritis: a 1-year follow-up study // Ann. Rheum. Dis. 2006. № 65. Р. 1208—1212.

10. McQueen F.M., Gao A., Ostergaard M. et al. High-grade MRI bone oedema is common within the surgical field in rheumatoid arthritis patients undergoing joint replacement and is associated with osteitis in subchondral bone // Ann. Rheum. Dis. 2007. № 66 (12). Р. 1581—1587.

11. McQueen F.M., Stewart N., Crabbe J. et al. Magnetic reso-nance imaging of the wrist in early rheumatoid arthritis reveals progression of erosions despite clinical improvement // Ann. Rheum. Dis. 1999. № 58 (3). Р. 156—163.

12. Ostergaard M., Peterfy C., Conaghan P. et al. OMERACT Rheumatoid Arthritis Magnetic Resonance Imaging Studies. Core set of MRI acquisitions, joint pathology definitions, and the OMERACT RA-MRI scoring system // J Rheumatol 2003. № 30. Р. 1385—1386 [Erratum in J. Rheumatol. 2004. 31. 198].

13. Treitl M., Panteleon A., Korner M. et al. Soft tissue manifestations of early rheumatic disease: imaging with MRI // Radiologe. 2006. № 46. Р. 677—680, 682—688.