Generalized tuberculosis in association with systemic lupus erythematosus on a background of methylprednisolone pulse therapy: difficulties of diagnostics and treatment
https://doi.org/10.20538/1682-0363-2017-2-187-194
Abstract
Systemic lupus erythematosus (SLE) and a high-dosage corticosteroid therapy both are risk factors of tuberculosis development. The clinical case presented demonstrates the difficulties of diagnostics and simultaneous therapy of comorbid diseases, which are followed by a multisystemic tuberculosis on the one hand, and a highly active SLE resulting from tubercular regimen on the other. Our experience shows the importance of antituberculosis drug prescription in accordance with a personal chemotherapy acceptability.
About the Authors
Olga V. Filinyuk
Siberian State Medical University
Russian Federation
Russian Federation
DM, Associate Professor, Head of the Phthisiology and Pulmonology Department
2, Moskow Тrakt, Tomsk, 634050
Larissa V. Eliseeva
Siberian State Medical University
Russian Federation
Russian Federation
Rheumatologist, Head of Rheumatology Department of Therapeutic Clinics
2, Moskow Тrakt, Tomsk, 634050
Olga A. Denisova
Siberian State Medical University
Russian Federation
Russian Federation
PhD, Assistant of the Hospital Therapy with a Сourse of Physical Rehabilitation and Sports Medicine Department
2, Moskow Тrakt, Tomsk, 634050
Catherine P. Stepanova
Tomsk Phthisiopulmonological Medical Center
Russian Federation
Russian Federation
Phthisiatrician
17/1, Str. R. Luksemburg, Tomsk, 634050
Peter N. Golubchikov
Tomsk Phthisiopulmonological Medical Center
Russian Federation
Russian Federation
Phthisiatrician, Deputy Сhief Мmedical Оfficer
17/1, Str. R. Luksemburg, Tomsk, 634050
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Review
For citations:
Filinyuk O.V., Eliseeva L.V., Denisova O.A., Stepanova C.P., Golubchikov P.N. Generalized tuberculosis in association with systemic lupus erythematosus on a background of methylprednisolone pulse therapy: difficulties of diagnostics and treatment. Bulletin of Siberian Medicine. 2017;16(2):187-194. (In Russ.) https://doi.org/10.20538/1682-0363-2017-2-187-194
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