Research objective. Identification of possibility of the modern pedagogical receptions in development of cognitive interest in students of a medico-technical profile at biology lessons.

Research techniques. The theoretical: the analysis of psychology and pedagogical and methodical literature on a research problem, the teoretiko-methodical analysis of a studied problem, development of methodical bases of its realization in biology training; approach to carrying out a lecture and practical training in biology with bionics elements. The empirical – supervision, conversation, questioning, manufacture of multimedia presentations for carrying out an interactive lecture and practical training and the analysis of results of work with them.

Material and methods. Students of the 1st course being trained in the direction of preparation 201000.62 – “Biotechnical systems and technologies” (bachelor degree).

Results. It is possible to carry the following to the positive moments: within interactive lecture there is a tendency to motivation change to educational activity with external on the internal; the pedagogical receptions based on interactivity, allow to keep attention of audience easier; using problem situations, it was possible to involve pupils in educational activity selectively; when using considered approach process of communication with audience gains more natural character, approaching developing relationship in teacher student system to cooperation.

It is possible to carry the next moments to the negative: process of teaching becomes more intense, deman­ding from the teacher of larger concentration on a training material, and constant readiness and ability to conduct discussion; the interactive format of giving of a training material sometimes possesses smaller informational characteristics; students are not always ready to such format of educational activity that is often shown in inability to carry on the free dialogue, inability to allocate the useful information; padding expenses are necessary from the teacher on maintaining of a subject matter during occupation.

Conclusion. As a result of the conducted research were revealed both positive, and the negative sides of interactive lecture. At an interactive method of teaching of biology, traditional reading of lecture was excluded. Students worked during all occupation, and the teacher had opportunity to estimate work of each student.

The adaptation of people to new production environment are often influenced by very unusual, excessive and harsh environmental factors, genetically inadequate to its nature. Human adaptation to the new production conditions can be summarized as a set of social and biological properties and characteristics needed to sustain the existence of the human body in a particular ecological environment.

It is necessary under the new conditions to achieve harmony of human interaction with the physical environment of their lives, adequate human nature. In addressing this fundamental problem of the 
primary role belongs to biomedical science, which should not so much to predict the appearance of the disease, how much help to preserve and improve the health of population. At the same time beco­ming increasingly clear that solving this problem adaptation theory plays a crucial role.

Adaptive features appear only in real life. It is in particular natural or artificial habitat capabilities of the body, when the survival and life require maximum mobilization and stress its potential adaptive capacity. Consequently, the property adaptation of living systems is, in fact, a measure of individual health.

An approach based on entropy methods for modeling complex systems, seems to be the most promising for integrated assessment of biological systems.

This work represented one of the possible approaches to providing the required computational resources for solving the complex data processing tasks in biomedicine. The proposed solution is based on four tightly interacted key components of modern high performance computational systems: high perfor­mance computational cluster, data processing center, specialized data store and protected telecommunication channels. The examples of tasks, which have been solved in the developed information environment, are given.

he purpose of the given research are situational tasks from the point of view of algorithms of their decision and application of computer technologies for realization of similar algorithms. In the beginning the concept of a situational task and an opportunity of their use for training medical students is considered. The analysis of existing situational clinical tasks is spent and classification of algorithms of the decision is resulted. The opportunity of application of computer technologies for realization of similar algorithms is considered. Among all existing algorithms of the decision one in which the algorithm can be applied to the decision of the same tasks of one class is especially allocated. The technology of construction of such algorithm is resulted and the description of a program complex which realizes such algorithm of the decision of situational tasks is given.

The purpose of the research is developing of approaches and criterias that allow obtaining individual health value. Existing methods of diagnosing may be divided into two categories: statistic methods and functional dependency, based on metabolic energy-information process that takes place in organism.

There is no doubt that wide spread statistic methods are beneficial and in most cases allow recognizing general trend of researched processes. But all statistic approaches share same drawback, they do not allow taking evincive conclusion while individual diagnosing and grading physician's impact in dynamics. Thus we face necessity for developing new ways of diagnosing, allowing individual health evaluating based on common trend. This task may be subdivided into: find common trend and recognize informative variables; identify anomalies and form homogeneous groups; apply methods to obtain average values, adequately revealing group functioning.

The article, based on systematic approach, describes technology presenting the results of observations and child’s body is presented as complex dynamical system, that includes all required elements for the sustained functioning under external environment condition. Energy-informative approach is used for synthesizing generalized criteria for evaluating the functioning of dynamical biosystems.

Given developed criteria and coefficients revealing the degree of tension in the body under normal functioning conditions. The average groups coefficient values are taken into consideration. Described energy-information approach enables determine state of normal or pathology functioning that may be crucial for children.

Application of energy-information approach to evaluate the functioning of dynamic systems, allows re­cognizing common trend of researched objects and obtain individual health values. Such tasks are faced by practical and evidence-based medicine – finding individual health values, based on analysis of common trend of functioning.

The effectiveness of a self regulation technique based on the biological feedback (BFB) has been studied during treatment in patients with Parkinson's desease. The specific recommendations for patients with Par­kinson's desease have been determined taking into account an appearance of the distinctive symptoms. The treatment method based on the BFB has been realized. The controllable physiological signals both electrocardiography and electromyography have been used in this method. The rehabilitation psycho-physiological complex “Reakor” has been used for the treatment and diagnostic procedures as well. The statistical analysis of the effectiveness of the self regulation method was performed. It has been shown the combination of medication and biofeedback training aids in the normalization of personal emotional parameters.

This paper is devoted to the modeling of the electrical system of the man’s cardiac tissue. The paper aims creating of the model, that geometrical structure is close to the actual geometry of the human heart. The processes occurring in the heart muscle are modeling by solving a system of nonlinear differential equations.

In the first stage, the conceptual problem can be formulated as follows: to create a model of the transmission of electrical signals, the geometrical structure of which is close to the actual geometry of the heart muscle.

The next stage of the technology cycle is a mathematical formulation of the problem. In this paper, it can be formulated as a solution to a system of nonlinear differential equations with given initial and boundary conditions. At the stage of constructing a mathematical model it is necessary to resort to some assumptions. In particular, you should consider the fact that the geometry created by the heart muscle will be enough simplified with the average size of a real heart and will be 54 × 54 × 70 mm.

At the stage of construction of computing algorithms to the mathematical model mathematical methods to its algorithmization was used. As considered in this paper, the system of nonlinear differential equations has no analytic solution, so to get the results it was decided to use a numerical method – the finite element method. To implement the finite element method mathematical modeling package COMSOL was selected.

In the next stage model was built using the COMSOL Multiphysics, including input of the physical parameters, initial and boundary conditions, the finite element mesh generation. As a result, a visual solution of the system FitzHugh–Nagumo has been received; graphs are showing the propagation of the electrical signal in the heart.

In the fifth stage, the representation, processing, analysis and interpretation of the results are given.

Thus, the task can be broken down by stages of computational experiment. Forecasting based on the constructed model at this stage is not possible due to the simplifications in the model, but a more detailed study of the problem can be done.

The goal of this paper is the analysis of information communication technologies using for professional competencies development for medical students. There are described two informational learning technologies: standard and developed in Tomsk.

Virtual learning environment Moodle is open source software which is developed for on-line education and installed in more than a dozen thousands educational institutions around the world including Russia. The Moodle provides students with rapid access to professional-oriented learning information via Internet any time and through any gadget. Using the Moodle a teacher can present different types of digital information, organize learning course, student’s knowledge and skills evaluation after structuring teacher’s knowledge. Rating approach is implemented in the Moodle very easy. Developed and develo­ping resources for the Moodle are located at the server http://simcenter.ssmu.ru.

Learning electronic health record (LEHR) is developing by Tomsk professional team and it is the integration of an electronic health record and a program for clinical subject. There are additional functions besides usual for paper medical record, for example: learning about specialized software, electronic re­ference books, and medical standard documents. Information and clinical competences are forming in LEHR at the same time what is the undoubted advantage for students. Now LEHR on pediatrics and neurology are testing before trial exploitation in the learning. Software for LEHR and information about virtual patients are located at the server http://students.umssoft.com.

The analysis and our experience have shown the possibilities of effective using the information communication technologies for development of informational and professional competencies of medical students in different subjects of educational program.

A possibility to unite different healthcare providers in one network was investigated and proved. We developed solution based on ISO 13606 archetype model and service oriented architecture to enable an exchange of semantically meaningful medical data within a network of healthcare providers. Application of a data model of the ISO 13606 standard for data modeling and XML data transformation allowed organizing data exchange in the regional healthcare network.

Our research is aimed to investigate the influence of breathing exercises and aqua-gymnastics on the adaptive capabilities of pregnant women in different trimesters of gestation.

The estimation of adaptive capabilities of the pregnant women organism was carried out on the basis of functional tests on breath-holding duration – Stange’s test (for inhalation) and Ghencea’s test (for exhalation) in the initial period, 11–19, 21–29 and 31–39 weeks periods of pregnancy.

To identify the adaptation strategies for pregnant women the method proposed by Ya.S. Pekker and A. Rotov was used, namely, the consideration of information measure as a measure of biological object preference behavior. Analysis of the results with information criterion of curve types using cluster analysis allowed to identify 4 standard types of adaptation strategies for pregnant women: adaptive, compensatory, compensatory-adaptive and maladaptive compensatory type of response. To estimate the adaptive capabilities of the respiratory system the ratio between the level of respiratory system functioning, its functional reserve and the degree of stress regulation mechanisms was considered.

The intensity of lipid peroxidation processes (LPO) in the blood serum of pregnant women was assessed by determining malondialdehyde (MDA) in the reaction with 2-thiobarbituric acid. Determination of vitamin D content in blood serum was estimated by fluorimetric method using spectrophotometer «Hitachi-85» (Japan) at an excitation wavelength of 295 nm and 320 nm fluorescence. Determination of the level of stress hormones (cortisol, insulin) in the blood serum of pregnant women was performed by radio ligand assay.

The following somatic diseases were registered among pregnant women applying to hospital: chronic tonsillitis, sinusitis, vasomotor rhinitis, bronchitis, bronchial asthma, hay fever, chronic pyelonephritis, atopic dermatitis. The next prenatal risks were revealed: morning sickness in I and II half of pregnancy, anemia, the threat of pregnancy termination, hypertension and hypotension.

The complex of breathing exercises and aqua-gymnastics was carried out as follows. Firstly the presence of somatic diseases and prenatal risk factors (ultrasound, CTG, Doppler) were confirmed. Then termina­ting breath tests were carried out, after which the complex of breathing exercises and aqua-gymnastics was put on.

Carrying out this complex by main group women allowed increasing their functional reserves level and forming a good adaptation to the various factors of external and internal environment, as indicated by the adaptive type of response in 64% of the cases. There was a gradual decline in the functional reserves of pregnant women with somatic morbidity and prenatal risk factors who did not make the complex of breathing exercises and aqua-gymnastics that indicates the possible worsening of somatic pathology. Subsequently, these women have a disease recurrence contributed to a further decrease in functional reserves, which led to the breakdown of adaptation in 35% of cases.

The performing of breathing exercises and aqua-gymnastics had a positive effect on the hormonal and metabolic status of pregnant women. In the first trimester cortisol concentration was significantly lower in women of main group and comparison group compared to control group. Against the background of the active respiratory training within the main group of women it was shown normalization of this hormone concentration in the blood serum up to the performance level of healthy mothers. Indices of insulin in the blood serum against the background of pregnancy also tended to increase, but they remained within the reference ranges.

Breathing exercises combined with aqua-gymnastics helped to increase the sensitivity to hormones and exerted a stimulating effect on the secretion of glucocorticoid effect.

In the main group of women against the background of the respiratory training in the third trimester of pregnancy it were identified lower rates of lipid peroxidation compared with those observed during pregnancy in the usual way (control group), which corresponded to women's health indicators. At the same time in the third trimester of pregnancy it was found a significant increase in the concentration of vitamin E in the blood serum of women from the main group compared to the control group (p < 0.001).

The complex of breathing exercises and aqua-gymnastics have a stimulating effect on metabolism, thereby it normalizes the level of antioxidant enzyme. During the breathing exercises process a direct correlation was revealed between the level of MDA and cortisol (r = 0.67) and between vitamin E and insulin (r = 0.61). These data allow suggesting the prospects for determining the concentration of MDA and vitamin E in the peripheral blood of pregnant women to determine the adaptive capability of the organism and the favorable course of pregnancy and childbirth.

It is possible that the complex of adaptive respiratory and aqua-gymnastics performing by pregnant women promotes more intensive penetration of oxygen from the blood to tissue, which leads to better oxidation of the substrate and hence reduce the concentration of MDA in women of main group. Timely addition of breathing exercises complex during pregnancy, as well as aqua-gymnastics, promotes restoration of redox enzymatic processes in the tissues, leading to improved utilization of fetal oxygen; contributes to Verigo–Bohr strengthening effect, intensive penetration of oxygen from the blood into tissues, resulting in the release of carbon dioxide. Accumulated carbon dioxide promotes active oxygen transportation to the fetus and increases the adaptive capabilities of the organism.

Thus, the experience of working with groups of pregnant women with somatic pathology and prenatal risk factors, allowed us to estimate the effectiveness of breathing exercises combined with aqua-gymnastics and develop a more sophisticated approach to the restoration of functional reserves due to the activation of natural mechanisms of recovery.

The results of this method were characterized by a decrease in cases of pregnant women hospitalization, decrease of the fetal hypoxia degree, the successful outcome of pregnancies. The usage of complex of breathing exercises combined with aqua-gymnastics, modulating antioxidant activity in the organism, can be a crucial factor in improving the functional reserves when there are any complications in pregnancy. In addition, there is the decrease in maternal mortality in 1.9 times.

Depth of activation reaction (α-activity suppression during the eyes-opening task) is considered to be an important quantitative characteristic of α-band brainwaves. Activation reaction was assessed from O1 and O2 leads in 31 male substance dependent subjects. In 7 cases it was measured twice: before and after α- or β-brainwave biofeedback training. The correlations were found between grade of α suppression in eyes-opening task and attitude towards disease and treatment, personality maturity, and level of pathological personality traits. Activation reaction was significantly improved by α-training and non-significantly diminished after β-1-training.

he problem is to translate medical knowledge into the philosophy of the specialist so that he has learned to see mentally not only the thinnest biological structures, but also to feel their displays in scales of a holistic organism. To achieve such effect, special translators are required. For their creation the biomedical knowledge is considered from the viewpoint of sciences about systems: cybernetics, synergetics, nonlinear dynamics, management theory. Examples: model of homeostasis support in terms of the management theory, the adaptation as a series of recombinations of functional systems in the space of compensatory-adaptive reactions, notion of an information resource of adaptive behavior, understanding of structural disorganization of a membrane of the red blood cells as of a universal model of reaction of a holistic organism. For substantiation the possibility to solve the task representation systemic world outlook and systems thinking are introduced, model of self-organization in the system of specialist knowledge and psychology of creative thinking have been involved.

Traditional methods of teaching in medical high school of informatics as computer sciences and statistics as a section of high mathematics contradict to requirements of modern applied medicine and a medical science. A research objective is revealing of the reasons of the given discrepancy and its elimination ways. Similar discrepancy was revealed earlier by foreign researchers studying efficiency of the statistic school programs. The revealed laws appeared to be extended to a technique of teaching of statistics in a high medical school. Pursuing this aim the tests of educational achievements developed by the author were applied on the students of medical and biologic department of the Siberian State Medical Universirty that trained on specialities of “biophysics" and “biochemistry". The fundamental problem of statistical education is that symbols used by these science concern to the objects, which students still have to design. As a substantiation of this conclusion serves the ontosemiotical approach to working out of the maintenance of a course. In the article there are considered the approaches to the permission of the given contradiction, based on the experience of teaching of statistics in foreign schools and on the wor­kings out of the author. In particular the conclusion about necessity of revision the tradition of using professional statistical packages and introduction of a special educational software. To working out the maintenance of a learning course it is offered to more widely apply the historical approach which concrete definition is represented by a principle of a guided reinvention.

The use of graphics in research works not only increases the speed of information transmission and increases the level of its understanding, but also contributes to the development of such important for professionals in any industry qualities of intuition and creative thinking. Methods of cognitive graphics significantly extend the capabilities of specialists any field of knowledge to identify the most informative parameters when processing the extensive data base and solving specific problems; detect sometimes radically new facts, radically changing their views known. A separate direction of cognitive graphics forms in medicine. Visualization of the current state of the object and the characteristic features provide continuous control over the condition of groups of persons or individual.

This work focuses on the identification of psychological and physiological characteristics of patients with various forms of bronchial asthma using the methods of visualization of multidimensional data.

Thus, the object of study are the physiological data of patients with bronchial asthma. Subject of research are the methods of cognitive graphics, namely, the methods of information presentation in the form of graphic images.

The aim of this work is to study the possibilities of applying the methods of cognitive graphics in the study of the physiological characteristics of patients with various forms of bronchial asthma. In the end, work has revealed a number of regularities for various forms of bronchial asthma using the methods of data visualization.

Major disabling factors in multiple sclerosis is motor disorders. Rehabilitation of such violations is one of the most important medical and social problems. Currently, most of the role given to the development of methods for correction of motor disorders based on accessing natural resources of the human body. One of these methods is the adaptive control with biofeedback (BFB). The aim of our study was the correction of motor disorders in multiple sclerosis patients using biofeedback training. In the study, we have developed scenarios for training rehabilitation program computer EMG biofeedback aimed at correction of motor disorders in patients with multiple sclerosis (MS). The method was tested in the neurological clinic of SSMU. The study included 9 patients with definite diagnosis of MS with the presence of the clinical picture of combined pyramidal and cerebellar symptoms. Assessed the effectiveness of rehabilitation procedures biofeedback training using specialized scales (rating scale functional systems Kurtzke; questionnaire research quality of life – SF-36, evaluation of disease impact Profile – SIP and score on a scale fatigue – FSS). In the studied group of patients decreased score on a scale of fatigue (FSS), increased motor control (SIP2), the physical and mental components of health (SF-36). The tendency to reduce the amount of neurological deficit by reducing the points on the pyramidal Kurtske violations. Analysis of the exchange rate dynamics of biofeedback training on EMG for trained muscles indicates an increase in the recorded signal OEMG from session to session. Proved a tendency to increase strength and coordination trained muscles of patients studied.

Positive results of biofeedback therapy in patients with MS can be recommended to use this method in the complex rehabilitation measures to correct motor and psycho-emotional disorders.

Background. Implementation of software for areas of interest retrieval in 3D medical images is described in this article. It has been tested against large volume of model MRIs.

Material and methods. We tested software against normal and pathological (severe multiple sclerosis) model MRIs from tge BrainWeb resource. Technological stack is based on open-source cross-platform solutions. We implemented storage system on Maria DB (an open-sourced fork of MySQL) with P/SQL extensions. Python 2.7 scripting was used for automatization of extract-transform-load operations. The computational core is written on Java 7 with Spring framework 3. MongoDB was used as a cache in the cluster of workstations. Maven 3 was chosen as a dependency manager and build system, the project is hosted at Github.

Results. As testing on SSMU's LAN has showed, software has been developed is quite efficiently retrieves ROIs are matching for the morphological substratum on pathological MRIs.

Conclusion. Automation of a diagnostic process using medical imaging allows to level down the subjective component in decision making and increase the availability of hi-tech medicine. Software has shown in the article is a complex solution for ROI retrieving and segmentation process on model medical images in full-automated mode.

We would like to thank Robert Vincent for great help with consulting of usage the BrainWeb resource.

The features of deposition of highly dispersed particles of smoke on nanoscale biological airway surface on the example of tobacco smoke are considering. A model of particle deposition of the nicotine gum along the way through the smoke inhaled. Obtain a solution of the equation for the diffusion flux changes deposited nano- and submicron particles through hydrodynamic boundary layer.

The particle deposition of nicotine gum on the airways by scanning the distribution of nanoparticles deposited using an atomic force microscope SobverPRO was experimentally studied. Patterns of distribution of nanoparticles dispersed smoke 4 species of tobacco in different parts of the respiratory tract were obtained. That allowed to talk about the absence of the effect of coagulation of the airway. It was established that the child as a passive smoker particle deposition diffusive flux of nicotine is proportionally higher than adult because the channel width is less than the airways than in adults.

Text abstract Mother’s and fetus’s health are very important in present time. With timely diagnosis perinatal pathology, birth injuries, antenatal stillbirths and newborn perinatal death can be prevented. At the moment in the world there are no complexes which enable monitoring of the fetus without any risk to his health. So the main aim of this work is development of hardware and software system to assess the functional status of the mother and fetus by the analysis of the signals recorded from the abdominal electrodes.

Objectives:

1) to formulate the requirements to noninvasive monitoring system and functional state assessment of mother and fetus.

2) to develop algorithms and software for monitoring system and functional state assessment of mother and fetus.

3) to determine fetus functional state at 32–33 week in women with uncomplicated pregnancies and in women with placental insufficiency in the compensation stage and subcompensation.

The system concept is based on fetal heart rate recognition and analysis. Fetal heart rate has been extracted from the mixed signals received from abdominal electrodes. This technique is passive for a body so there is no research time limit. Device for simultaneous registration of fetal and maternal electrocardiogram is high sensitive bioamplifier with low level of intrinsic noises, high input resistance and suppression of inphase noises more than 80 DB. Digital processing of a signal is carried out by microcontroller of the registration module and personal computer. Preprocessing is carried out in microcontroller by receiving signals from the analog-to-digital converter on the increased sampling rate, digital filtering, decimation.

With the help of the developed complex two-stage study was conducted. At first stage the fetal cardiointervalogram (i.e. fetus heartbeat period and the distribution pattern of these intervals in time) was studied. Second stage was carried out to search additional criteria of fetal functional state assessment with placental insufficiency in the pregnant with hyperandrogenism in the third trimester.

As result, it was defined, that parameters of heart rate structure at 32–35 weeks of gestation allows to assess the risk of functional disorders and development of fetus hypoxia with sensitivity Se = 80% and specificity Sp = 73%.

There is the big issue in medical education which is students don’t have enough skills. Often even with theoretical knowledge graduate medical students need to improve their skills by working with patients. Obviously it can be a risk for patients and takes quite long time. This situation could be changed with applying simulation technologies in medical education. Medical education with virtual simulators allows reducing the time of skills development and improving the quality of training. The aims of this work are developing informational model and creating clinical scenarios of emergency states in the Medical Simulation Center.

Objectives:

– to analyze the process of scenario conducting;

– to create clinical scenarios of emergency states (anaphylactic shock, hypovolemic shock, obstructive shock) with specialist’s help.

The scenarios consist of sections such as main aim, skills, required mannequins, preparation of the mannequins, preparation of medical equipment and instruments for the scenario, preparation of special materials, scenario description, guide for operator, information for trainees.

By analyzing the process of scenario conducting the key participants were defined who are operator, assistant, trainer, trainees. Also the main scenario stages were defined. Based on the stages diagram of variants of scenario conducting was designed.

As an example there are fragments of scenario “Obstructive shock – a pulmonary embolism” in this article. Learn skills are cognitive, technical, social ones.

Results. This paper presents an analysis of the clinical scenario conducting. Information model was developed which based on object-oriented decomposition. The model is the diagram of variants of scenario conducting. Scenario’s structure for emergency states was formulated. The scenarios are anaphylactic shock, hypovolemic shock, obstructive shock (pulmonary embolism, tension pneumothorax), pulmonary edema, hypertensive crisis, respiratory distress syndrome of the newborn, meconium aspiration syndrome.

Moodle (Modular Object-Oriented Dynamic Learning Environment) is the system developed by the English-speaking community around the world for more than 10 years, supports both, offline and online training. In most cases, Moodle is used to support and connect learning face-to-face with online training, as well as with other types of learning. Moodle allows you to ask all sorts of questions and assess responses in a variety of ways. The central concept of Moodle is a course in which one or more teachers offer students resources (such as files, folders, Web pages) and participate in interactive activities (such as forums, wikis, blogging, lessons, seminars, assignments, examinations). Students and teachers can change roles, mutually assess each other, share knowledge on the topics of study in the glossary and database system.

In the English-speaking world, there are public sites with detailed documentation on Moodle, which is constantly verified and modified in accordance with emerging new versions of the system; Russian versions do not have public sites with detailed translation of the English-language documentation. On what and to whom you want to perform actions in the daily practice of the modern versions, only the barest of outlines on paid seminars and presentations to those who started the implementation of Moodle in your organization are given. And this despite the fact that the system has a great variety of Moodle (over 500) settings with different levels of functionality to be performed, to maintain and develop specially organized by the team of specialists. The question is not only about creating a training course in Moodle. It's about maintaining the health of the system within the institution, such as a University. Under the "health maintenance" means: availability and preservation of up-to-date documentation on system and manuals on Moodle separately for administrators, managers, teachers and students at their level, training consultants for each level and help Moodle users to carry out their work in an ever-growing versions of this system. The second important feature of the group is to perform administrative work on authentication of users and transfer/expulsion from the course assignment and modification of the roles, responsibilities and opportunities of users of Moodle, backing up, and take the necessary measures to ensure the confidentiality and security, implement the necessary measures for transfer students with the course on the course, at the end of the semester or school year, maintaining the required accounting and reporting documents, and so on.

This article tries to understand the enormous potential of Moodle in transposition on the duties of the officers of the ad hoc group support this system within the University as a whole. Only competent and timely response to the needs of the teachers involved in the conduct of training courses in Moodle environment can allow to achieve a high level of educational services.

Research objective: improvement of screening systems of diagnostics of socially significant diseases by modeling of volt-ampere characteristics of bioactive points (BAP) and classification of received models by means of computer technologies.

Research problems:

– development of structurally functional model of electric conductivity of a biomaterial in abnormal zones (in the field of acupuncture points);

– development of a method of formation of space of the informative signs intended for qualifiers of a functional condition of a biomaterial.

Material and methods. For the solution of objectives methods of the theory of linear electric chains, methods of mathematical modeling were used. When modeling conductivity of a biomaterial as tools Matlab 8.0 was used.

For modeling of the volt-ampere characteristic of BAP it is offered to use structural-functional models with diode-resistive cells of symmetric structure. The method of formation of space of the informative signs intended for qualifiers of a functional condition of a biomaterial, the volt-ampere of characteristics of a biomaterial consisting in registration in each bioactive point by impact on them by the constant tension stabilized on level in the range from –15 V to +15 V, changed with a step in 1 V is developed. By comparison of characteristic points of the volt-ampere characteristic and parameters of structural-functional model the vector of informative signs intended for the neuronetwork qualifier is formed.

Results. The structural-functional model of conductivity of a biomaterial on the basis of diode-resistive cells is constructed. The factorial analysis of volt-ampere characteristics of biomaterials on the basis of which it is shown is carried out that for creation of structural-functional model of conductivity of a biomaterial there are enough seven diode-resistive cells.

Conclusions. The received results allow to construct classifying modules for preclinical diagnostics of socially significant diseases or the diseases masked by a functional condition of an organism or professional activity, for example, diagnostics of pyelonephritis at pregnant women. For diagnostics it is enough to enter BAР (30 values) then the program will receive seven values of the ohmic resistance corresponding to model of a bioimpedance which are used as an entrance vector of informative signs in the neuronetwork qualifier into the computer of coordinate of the volt-ampere characteristic.

Researched physiological mechanisms of development of orthostatic tachycardia syndrome (POTS) on the basis of a complex spectral structure analysis of heart rate variability (HRV), its nonlinear behavior in relationship to energy oscillations, baroreflex and parasympathetic activity. There were several stages of research.

The first stage: created the method of spectral analysis of individual components of Very Low Frequency (VLF). On the basis of comparative Fast Furrier Transform data with Welch filters, autoregression, continuous wavelet analysis and Hilbert–Huang transform, for the first time it was shown that VLF has separate 200, 100 and 50 s oscillations (VLF200, VLF100, VLF50).

The second stage: for evaluation of physiological properties of separate oscillations, was analyzed VLF structure in three groups of patients (100 subjects): with a predominance of parasympathetic activity (HF) in the HRV spectrum; with a dominance of 10 s oscillations (LF); with a severe depression of 
energy in all components of the spectrum. It was established that the individual components of VLF (VLF100 and VLF50) have a certain stability and partial independence from the changes of peripheral autonomic indices (LF/HF) at loads of low intensity.

The third stage: at an active orthostatic test, 20 subjects with orthostatic tachycardia were researched in a comparison to a control group of 20 subjects without tachycardia.

Analyzed the specifics of the VLF structure (VLF100 and VLF50) alone and in a conjunction with the LF and HF, as well as heart rate and blood pressure in subjects with orthostatic tachycardia with a predominance of parasympathetic activity at functional tests of low intensity (seven-test, deep breathing) and at an active orthostatic test. Based on these studies it was concluded that the individual components in the VLF structure (VLF100, VLF50) can demonstrate reciprocal relationships at a load among themselves and in the LF/HF ratio, and play an adaptive role in the mechanisms of autonomic provision.

Revealed the importance of VLF and its components 100 and 50 s oscillations at an orthostatic test in the prognosis of orthostatic tachycardia development. In patients with dysautonomia at high level of VLF100 power, or high VLF50 indices, tachycardia did not develop. In this case, VLF and its component parts did an important adaptive function and conversely, the low VLF50 indices contribute to orthostatic tachycardia.

In the proposed model of the descending neurosomatic control of autonomic regulation of HRV a very important role plays both neurogenic ways of regulation, and neuro-hormonal-metabolic ways, manifested in the complex VLF structure. Regarded the choice of ways and optimal neurosomatic models of regulation at POTS.

Phenomenon of thought and its’ interpretations at the different cultural and historical stages are in focus of the paper. The research is aimed at reasoning of new interpretation of thought revealed as a result of cognitive science and convergent technologies transdisciplinary research.

Transdisciplinary research of thought in cognitive science is achieved with the unity of method, which is the systemic-evolutionary approach.

The research is based on thought analysis in philosophy, cognitive psychology, cognitive linguistics, artificial intelligence science, thus mainly on transdisciplinary research of thought in cognitive science.

The paper represents the approach of cognitive science and NBIC (Nano-, Bio-, Information and Cognitive) technologies implementing transdisciplinary research of thought and intelligence.

It is shown that the transdisciplinary approach is based on new ontology, called holistic, and on nonclassical epistemology. Answering the raised question of the outcome of thought transdisciplinary research comparing to specifically scientific and philosophic, it is reasoned that cognitive science studies thought at the higher level of complexity, considering simultaneously several order parameters characterizing this complex nonlinear phenomenon.

This research has been aimed to carry out a study of peculiarities that arise in a numerical simulation of the electrical impedance tomography (EIT) problem. Static EIT image reconstruction is sensitive to a measurement noise and approximation error. A special consideration has been given to reducing of the approximation error, which originates from numerical implementation drawbacks. This paper presents in detail two numerical approaches for solving EIT forward problem. The finite volume method (FVM) on unstructured triangular mesh is introduced. In order to compare this approach, the finite element (FEM) based forward solver was implemented, which has gained the most popularity among researchers. The calculated potential distribution with the assumed initial conductivity distribution has been compared to the analytical solution of a test Neumann boundary problem and to the results of problem simulation by means of ANSYS FLUENT commercial software. Two approaches to linearized EIT image reconstruction are discussed. Reconstruction of the conductivity distribution is an ill-posed problem, typically requiring a large amount of computation and resolved by minimization techniques. The objective function to be minimized is constructed of measured voltage and calculated boundary voltage on the electrodes. A classical modified Newton type iterative method and the stochastic differential evolution method are employed. A software package has been developed for the problem under investigation. Numerical tests were conducted on simulated data. The obtained results could be helpful to researches tackling the hardware and software issues for medical applications of EIT.